Active Recombinant Mouse Interleukin 17D
| Cat.No. : | Il17d-645M |
| Product Overview : | RecombinantMouse Il17d protein was expressed in E. coli. Ala25-Arg205. |
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| Cat. No. : | Il17d-645M |
| Description : | TheInterleukin 17 (IL-17) family proteins, comprising six members (IL-17, IL-17Bthrough IL-17F), are secreted, structurally related proteins that share a conservedcysteine-knot fold near the C-terminus, but have considerable sequencedivergence at the N-terminus. With the exception of IL-17B, which exists as anon-covalently linked dimer, all IL-17 family members are disulfide-linked dimers.IL17 family proteins are pro-inflammatory cytokines that induce localcytokine production and are involved in the regulation of immune functions. |
| Source : | E. coli |
| Form : | Lyophilizedfrom a 0.2 um filtered solution in Acetonitrile and TFA with BSA as a carrierprotein. |
| N-terminalSequence : | Ala25 |
| MolecularWeight : | 20 kDa (monomer) |
| Activity : | Measuredby its ability to bind rmIL17-BR/Fc Chimera in a functional ELISA. |
| Endotoxin Level : | <1.0EU per 1μg of the protein by the LAL method. |
| Purity : | >95%,by SDS-PAGE under reducing conditions and visualized by silver stain. |
| Reconstitution : | Reconstituteat 100μg/mL in sterile 4 mM HCl containing at least 0.1% human or bovineserum albumin. |
| Storage : | Use amanual defrost freezer and avoid repeated freezethaw cycles. 12 months from date of receipt, -20 to -70°C as supplied.1 month, 2 to 8°C under sterile conditions after reconstitution. 3months, -20 to -70°C under sterile conditions after reconstitution. |
| Gene Name : | Il17d interleukin 17D [ Musmusculus ] |
| Official Symbol : | Il17d |
| Synonyms : | Il17d; interleukin17D; Il27a; IL-17D; AI462269; interleukin 27A |
| Gene ID : | 239114 |
| mRNA Refseq : | NM_145837 |
| Protein Refseq : | NP_665836 |
| UniProt ID : | Q8K4C4 |
| Chromosome Location : | 14 |
| Function : | molecular_function |
Products Types
| ◆ Lysates | ||
| IL17D-852HCL | Recombinant Human IL17D cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionNeuroinflammation models, neuronal cell assays, and CNS analysis explore IL17D's role in neurological contexts.
Tumor xenografts, immune cell infiltration analysis, and gene expression profiling dissect IL17D's role in cancer.
Functional assays, knockout models, and gene expression analyses distinguish IL17D's unique roles.
Microbiota sequencing, gnotobiotic models, and immune cell profiling investigate IL17D-gut microbiota interactions.
Animal models, patient samples, and genetic studies elucidate IL17D's involvement in autoimmune diseases.
Wound healing assays, tissue regeneration studies, and histological analyses examine IL17D's effects on tissue repair.
Signal transduction assays, phosphoproteomics, and cytokine profiling reveal IL17D's signaling pathways.
Cell culture models, infection assays, and epithelial barrier assessments uncover IL17D's impact on host defense.
Flow cytometry, chemotaxis assays, and adoptive transfer experiments probe IL17D-mediated immune responses.
Therapeutic antibody testing, RNA interference, and animal disease models validate IL17D as a potential therapy.
Customer Reviews (3)
Write a reviewEffective in Th9 differentiation.
Suitable for ELISA.
High bioactivity.
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