Active Native Human MUC1
| Cat.No. : | MUC1-376H |
| Product Overview : | Human MUC1 was purified from Human Ascites Fluid |
- Specification
- Gene Information
- Related Products
- Download
| Description : | Cancer Antigen 15-3 (CA 15-3) is used as a tumor marker to monitor a patients response to breast cancer treatment and to watch for breast cancer recurrence. |
| Source : | Human Ascites Fluid |
| Species : | Human |
| Form : | Liquid in phosphate buffered saline, pH 7.4, with 0.05% sodium azide. |
| Bio-activity : | > 5,000 IU/mL (ELISA) |
| Purity : | Control Grade |
| Applications : | Diagnostic Controls, Calibrators & Standards; Immunoassays; Clinical Chemistry; Testing/Assay Validation; Life Science; Manufacturing; Tumor Markers |
| Storage : | Store at -20°C |
| Gene Name : | MUC1 mucin 1, cell surface associated [ Homo sapiens ] |
| Official Symbol : | MUC1 |
| Synonyms : | EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; DF3 antigen; H23 antigen; Medullary cystic kidney disease, autosomal dominant; breast carcinoma-associated antigen DF3; cancer antigen 15-3; carcinoma-associated mucin; episialin; krebs von den Lungen-6; mucin 1, transmembrane; peanut-reactive urinary mucin; polymorphic epithelial mucin; tumor associated epithelial mucin; tumor-associated epithelial membrane antigen |
| Gene ID : | 4582 |
| mRNA Refseq : | NM_001018016 |
| Protein Refseq : | NP_001018016 |
| MIM : | 158340 |
| UniProt ID : | P15941 |
| Chromosome Location : | 1q21 |
| Pathway : | IL-7 Signaling Pathway, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; O-linked glycosylation, organism-specific biosystem |
| Function : | p53 binding; protein binding; transcription cofactor activity |
Products Types
| ◆ Recombinant Protein | ||
| MUC1-386H | Recombinant Human MUC1 Protein, Fc-tagged | +Inquiry |
| MUC1-5745H | Recombinant Human MUC1 Protein, GST-tagged | +Inquiry |
| MUC1-2662H | Recombinant Human MUC1 protein(31-100 aa), C-His-tagged | +Inquiry |
| MUC1-448H | Recombinant Human MUC1 protein(Met 1-Gly 167) | +Inquiry |
| MUC1-2661H | Recombinant Human MUC1 protein(31-150 aa), C-His-tagged | +Inquiry |
| ◆ Native Protein | ||
| MUC1-4770H | Active Native Human MUC1 Protein | +Inquiry |
| MUC1-135B | Native Bovine MUC1 Protein | +Inquiry |
| ◆ Lysates | ||
| MUC1-1980HCL | Recombinant Human MUC1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionThe MUC1 protein consists of a short extracellular region, a transmembrane region, and a long intracellular region. The extracellular region is rich in sugar chains, which make the MUC1 protein adherent.
In cancer, the expression of the MUC1 protein usually increases abnormally and changes in glycosylation occur. This can affect cell adhesion, proliferation, and invasion, promoting the spread and metastasis of cancer cells.
Yes, the MUC1 protein is closely related to the immune system. In some cases, abnormal expression of the MUC1 protein may interfere with the function of immune cells, thereby reducing the immune response.
MUC1 protein is overexpressed in many types of cancer, including breast, stomach, ovarian, and others. Therefore, the MUC1 protein can be a potential target for cancer diagnosis and treatment.
The MUC1 protein mainly plays the role of protecting and lubricating the mucosal surface. It prevents bacteria and other pathogens from entering our body, while also helping to maintain cell-to-cell adhesion.
MUC1 protein may be associated with a number of other diseases, such as lung infections and inflammatory bowel disease. However, the research related to cancer is more extensive and in-depth.
Customer Reviews (3)
Write a reviewIt is suitable for crystallography research and has good crystallinity.
Target immune responses can be successfully induced.
Enzymatic experiments showed that the catalytic efficiency was high
Ask a Question for All MUC1 Products
Required fields are marked with *
My Review for All MUC1 Products
Required fields are marked with *
Inquiry Basket
