Recombinant Protease Activated Receptor 2 (PAR2) Homo sapiens (Human) Recombinant protein

F2RL1; F2-RL1; GPR11; PAR2; Coagulation Factor II(thrombin)receptor-Like 1; G-protein coupled receptor 11; Thrombin receptor-like 1

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Overview
Properties
  • Source Prokaryotic expression, Host E.coli
  • Endotoxin Level<1.0EU per 1µg (determined by the LAL method)
  • Subcellular LocationMembrane
  • Molecular Mass 13.8kDa, Accurate 14kDa(Analysis of differences refer to the manual)
  • Residues & TagsVal309~Tyr397 with N-terminal His Tag
  • Buffer Formulation20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
  • Traits Freeze-dried powder, Purity > 95%
  • Isoelectric Point10.0
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  • Recombinant Protease Activated Receptor 2 (PAR2) Packages (Simulation)
  • Recombinant Protease Activated Receptor 2 (PAR2) Packages (Simulation)
  • Recombinant Protease Activated Receptor 2 (PAR2) Figure . Gene Sequencing (extract)
  • RPA852Hu01.jpg Figure. SDS-PAGE
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Sequence

Usage

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Storage

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

Stability

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Citations

  • Biomarkers of Fibroproliferative Healing in Fibrosing Idiopathic Interstitial PneumoniasPubMed: PMC3551240
  • Cathepsin S, a new pruritus biomarker in clinical dandruff/seborrhoeic dermatitis evaluationOnlinelibrary: exd.12357
  • PAR2, IL4R, TGFβ and TNFα in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosisPubmed:Pmc4079423
  • Proteinase-activated receptor 2 and disease biomarkers in cerebrospinal fluid in cases with autopsy-confirmed prion diseases and other neurodegenerative diseasesPubMed: 25886404
  • Epithelial Cell-Derived Cytokines Contribute to the Pathophysiology of Eosinophilic Chronic RhinosinusitisPubmed:26540312
  • Cathepsin S Alters the Expression of Pro-Inflammatory Cytokines and MMP-9, Partially through Protease—Activated Receptor-2, in Human Corneal Epithelial CellsPubmed: 30423938
  • Whitening effects of cosmetic formulation in the vascular component of skin pigmentationPubmed: 31074159
  • Interstitial Score and Concentrations of IL-4R¦Á, PAR-2, and MMP-7 in Bronchoalveolar Lavage Fluid Could Be Useful Markers for Distinguishing Idiopathic Interstitial?¡­33924683

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