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Recombinant Plasmodium falciparum Serine-repeat antigen protein (SERA), partial

Recombinant Plasmodium falciparum Serine-repeat antigen protein (SERA), partial

Code	CSB-YP886965EWP
MSDS	MSDS
Size	Pls inquire
Source	Yeast
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Code	CSB-EP886965EWP
MSDS	MSDS
Size	Pls inquire
Source	E.coli
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Code	CSB-EP886965EWP-B
MSDS	MSDS
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP886965EWP
MSDS	MSDS
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP886965EWP
MSDS	MSDS
Size	Pls inquire
Source	Mammalian cell
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Purity

>85% (SDS-PAGE)

Target Names

SERA

Uniprot No.

Q9TY95

Alternative Names

SERA; PFB0340c; Serine-repeat antigen protein; 111 kDa antigen; p126

Species

Plasmodium falciparum (isolate 3D7)

Protein Length

Partial

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose, pH 8.0

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Plays an essential role during the asexual blood stage development by controlling the kinetics of merozoite egress from host erythrocytes. Specifically, prevents premature rupture of the parasitophorous vacuole and host erythrocyte membranes.; May prevent merozoite phagocytosis by host monocytes via interaction with host VTN at the merozoite surface. Plays a role in parasite growth.; Protease activity is controversial. Has been shown in a number of studies to have protease activity towards a synthetic peptide in vitro. Has also been shown to lack protease activity towards a synthetic peptide in vitro.

Gene References into Functions

Disruption of the SERA5 gene results in a dramatic egress and replication defect characterised by premature host cell rupture and the failure of daughter merozoites to efficiently disseminate. PMID: 28683142
SERA5 plays an indispensable role in the P. falciparum blood-stage life cycle. PMID: 25599609
These results reinforce the role of PfSERA5 for the intra-erythrocytic development of malaria parasite and show the role of carboxy terminal ~6kDa fragments in the regulation of PfSERA5 activity. PMID: 24769454
Data indicte that children with Burkitt lymphoma (BL) in Ghana have lower antibodies to SE36 antigen. PMID: 21630256

Subcellular Location

[Serine-repeat antigen protein 5]: Parasitophorous vacuole.; [p18]: Secreted.; [p25n]: Secreted.; [p25c]: Secreted.; [p47]: Secreted. Cell membrane; Peripheral membrane protein; Extracellular side.; [p50]: Secreted.; [p56]: Secreted.

Protein Families

Peptidase C1 family

Database Links

KEGG: pfa:PFB0340c

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