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TSH-alpha Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P01215 |
|---|---|
| Clone Names | 80821097 |
| Gene ID | 1081 |
|---|---|
| Other Names | Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, CG-alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain, CGA |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CGA |
|---|---|
| Function | Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. |
| Cellular Location | Secreted |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The four human glycoprotein hormones chorionicgonadotropin (CG), luteinizing hormone (LH), follicle stimulatinghormone (FSH), and thyroid stimulating hormone (TSH) are dimersconsisting of alpha and beta subunits that are associatednoncovalently. The alpha subunits of these hormones are identical,however, their beta chains are unique and confer biologicalspecificity. The protein encoded by this gene is the alpha subunitand belongs to the glycoprotein hormones alpha chain family.
References
Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)Panicker, V., et al. Am. J. Hum. Genet. 87(3):430-435(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Robinson, N., et al. Clin. Lab. 56 (5-6), 197-206 (2010) :Bjerner, J., et al. Scand. J. Clin. Lab. Invest. 69(8):873-879(2009)
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