Actin (ACTB/ACTC) Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P68032 |
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Clone Names | 70716021 |
Gene ID | 70 |
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Other Names | Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ACTC1, ACTC |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP1491c was selected from the Center region of human ACTB/ACTC. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ACTC1 |
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Synonyms | ACTC |
Function | Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. |
Cellular Location | Cytoplasm, cytoskeleton. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. ACTB/ACTC are nonmuscle cytoskeletal actins and major constituents of the contractile apparatus. Defects in ACTB are a cause of juvenile-onset dystonia. Defects in ACTC have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).
References
Villebeck,L., Biochemistry 46 (44), 12639-12647 (2007)Avizienyte,E., Exp. Cell Res. 313 (15), 3175-3188 (2007)Bouldin,A.A., Muscle Nerve 35 (2), 254-258 (2007)
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