| Name | 14-3-3 (Ser58) Antibody |
|---|---|
| Supplier | ABBIOTEC |
| Catalog | 252518 |
| Prices | $385.00 |
| Sizes | 100 µl |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Applications | ELISA WB IHC |
| Species Reactivities | Bovine |
| Antigen | KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Ser58 of rat 14-3-3. |
| Purity/Format | Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography. |
| Description | 14-3-3 protein beta/alpha (14-3-3) is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. p1433-58 binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. p1433-58 binding generally results in the modulation of the activity of the binding partner. p1433-58 is a negative regulator of osteogenesis. Recent work has demonstrated that the dimeric status of the 14-3-3 protein is regulated by site-specific serine phosphorylation. |
| Gene | Ywhab |
| Supplier Page | Shop |