Gene Symbol | Ywhab |
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Entrez Gene | 56011 |
Alt Symbol | - |
Species | Rat |
Gene Type | protein-coding |
Description | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
Other Description | 14-3-3 protein beta-subtype|14-3-3 protein beta/alpha|3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide|KCIP-1|prepronerve growth factor RNH-1|protein kinase C inhibitor protein 1|tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide|tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma|tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide|tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide|tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide|tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide|tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide |
Swissprots | P35213 |
Accessions | EDL96554 EDL96555 EDL96556 P35213 BC076502 AAH76502 D17446 BAA04260 FQ214109 FQ229978 S55223 AAA13843 S83440 AAB50874 NM_019377 NP_062250 |
Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2 (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Melanosome {ECO:0000250}. |
Top Pathways | Cell cycle, Oocyte meiosis, Viral carcinogenesis, PI3K-Akt signaling pathway, Epstein-Barr virus infection |
14-3-3 beta/alpha Antibody - NB100-665 from Novus Biologicals
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14-3-3-Protein-Antibody - AN1075 from Abgent, a WuXi AppTec company
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Phospho-Ser58-14-3-3-Protein-Antibody - AN1079 from Abgent, a WuXi AppTec company
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14-3-3 antibody - GTX82746 from GeneTex
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YWHAB Antibody - abx116383 from Abbexa
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14-3-3 protein beta/alpha (C-term) antibody - AP08607PU-N from Acris Antibodies
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14-3-3 protein beta/alpha pSer58 antibody - AP08608PU-N from Acris Antibodies
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14-3-3 (phospho Ser58) Antibody - 50-231 from ProSci
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14-3-3 Antibody - 50-178 from ProSci
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14-3-3 (Ser58) , Polyclonal Antibody - MBS502001 from MyBioSource
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14-3-3 Protein Antibody - 253107 from ABBIOTEC
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14-3-3 (Ser58) Antibody - 252518 from ABBIOTEC
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14-3-3 beta Polyclonal Antibody - PA1-4647 from Thermo Fisher Scientific
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14-3-3 Protein , Polyclonal Antibody - MBS502002 from MyBioSource
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14-3-3 Antibody - 612-401-D01 from Rockland Immunochemicals Inc
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14-3-3 β monoclonal antibody (4E1) - ADI-KAM-CC014-E from Enzo Life Sciences
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YWHAB Antibody - CSB-PA026285GA01HU from Cusabio
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Anti-14-3-3 Protein (OAPC00020) - OAPC00020 from Aviva Systems Biology
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14-3-3 Protein Antibody (Phospho-Ser58) (OAPC00178) - OAPC00178 from Aviva Systems Biology
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anti-14-3-3 phospho (Ser58) antibody - ARG52215 from Arigo Biolaboratories |
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anti-14-3-3 antibody - ARG52214 from Arigo Biolaboratories |
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14-3-3 protein beta/alpha (C-term) antibody - TA309071 from Acris Antibodies
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Anti-Phospho-14-3-3 (Ser58) antibody (KLH) - STJ120001 from St John's Laboratory Ltd
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Anti-14-3-3 antibody (KLH) - STJ120000 from St John's Laboratory Ltd
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14-3-3 protein beta/alpha antibody - TA309072 from Acris Antibodies
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