| Gene Symbol |
Ywhab
|
| Entrez Gene |
56011
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
|
| Other Description |
14-3-3 protein beta-subtype|14-3-3 protein beta/alpha|3-monooxygenase/tryptophan 5 monooxygenase activation protein beta polypeptide|KCIP-1|prepronerve growth factor RNH-1|protein kinase C inhibitor protein 1|tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta polypeptide|tryosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma|tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein beta polypeptide|tyrosine 3-monooxgenase/tryptophan 5 monooxgenase activation protein, beta polypeptide|tyrosine 3-monooxgenase/tryptophan 5-monooxgenase activation protein, beta polypeptide|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide|tyrosine 3/tryptophan 5 -monooxygenase activation protein beta polypeptide|tyrosine 3/tryptophan 5 -monooxygenase activation protein, beta polypeptide
|
| Swissprots |
P35213
|
| Accessions |
EDL96554 EDL96555 EDL96556 P35213 BC076502 AAH76502 D17446 BAA04260 FQ214109 FQ229978 S55223 AAA13843 S83440 AAB50874 NM_019377 NP_062250
|
| Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Melanosome {ECO:0000250}.
|
| Top Pathways |
Cell cycle, Oocyte meiosis, Viral carcinogenesis, PI3K-Akt signaling pathway, Epstein-Barr virus infection
|