Anti-DOK1 antibody

• Supplier: Abcam
• Catalog: ab8112
• Prices: $384.00
• Sizes: 100 µg
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB ICC/IF ICC/IF IP
• Species Reactivities: Human
• Antigen: Synthetic peptide, corresponding to amino acids 425-439 of Human DOK1 (Peptide available as ab39756
• Blocking Peptide: Human DOK1 peptide
• Description: Rabbit Polyclonal
• Gene: DOK1
• Conjugate: Unconjugated

Product images

All lanes : Anti-DOK1 antibody (ab8112) at 1 µg/mlLane 1 : Jurkat cell lysatesLane 2 : THP-1 cell lysateObserved band size : 62 kDa (why is the actual band size different from the predicted?)

ab8112 at 2µg/ml staining DOK1 in K562 cells by ICC/IF

Product References

Epstein-Barr virus down-regulates tumor suppressor DOK1 expression. - Epstein-Barr virus down-regulates tumor suppressor DOK1 expression.

Siouda M, Frecha C, Accardi R, Yue J, Cuenin C, Gruffat H, Manet E, Herceg Z, Sylla BS, Tommasino M. PLoS Pathog. 2014 May 8;10(5):e1004125.

A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through - A crucial role for DOK1 in PDGF-BB-stimulated glioma cell invasion through

Barrett A, Evans IM, Frolov A, Britton G, Pellet-Many C, Yamaji M, Mehta V, Bandopadhyay R, Li N, Brandner S, Zachary IC, Frankel P. J Cell Sci. 2014 Jun 15;127(Pt 12):2647-58.

Dok1 and Dok2 proteins regulate natural killer cell development and function. - Dok1 and Dok2 proteins regulate natural killer cell development and function.

Celis-Gutierrez J, Boyron M, Walzer T, Pandolfi PP, Jonjic S, Olive D, Dalod M, Vivier E, Nunes JA. EMBO J. 2014 Sep 1;33(17):1928-40.

Transcriptional regulation of the human tumor suppressor DOK1 by E2F1. - Transcriptional regulation of the human tumor suppressor DOK1 by E2F1.

Siouda M, Yue J, Shukla R, Guillermier S, Herceg Z, Creveaux M, Accardi R, Tommasino M, Sylla BS. Mol Cell Biol. 2012 Dec;32(23):4877-90.

Feedback circuits monitor and adjust basal Lck-dependent events in T cell - Feedback circuits monitor and adjust basal Lck-dependent events in T cell

Schoenborn JR, Tan YX, Zhang C, Shokat KM, Weiss A. Sci Signal. 2011 Sep 13;4(190):ra59.

Src-like adaptor protein (SLAP) is upregulated in antigen-stimulated mast cells - Src-like adaptor protein (SLAP) is upregulated in antigen-stimulated mast cells

Park SK, Qiao H, Beaven MA. Mol Immunol. 2009 Jun;46(10):2133-9.