| Gene Symbol |
YWHAG
|
| Entrez Gene |
7532
|
| Alt Symbol |
14-3-3GAMMA, PPP1R170
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
|
| Other Description |
14-3-3 gamma|14-3-3 protein gamma|KCIP-1|protein kinase C inhibitor protein 1|protein phosphatase 1, regulatory subunit 170|tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
|
| Swissprots |
P61981 Q6FH52
|
| Accessions |
EAW71804 P61981 AB024334 BAA85184 AF142498 AAD48408 AK024230 BAG51276 AK293505 BAG56989 AK295029 BAG58085 BC020963 AAH20963 BI495132 CR541904 CAG46702 CR541925 CAG46723 DC343104 NM_012479 NP_036611
|
| Function |
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. {ECO:0000269|PubMed:16511572}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|
| Tissue Specificity |
Highly expressed in brain, skeletal muscle, and heart. {ECO:0000269|PubMed:10486217}.
|
| Top Pathways |
Cell cycle, Oocyte meiosis, Viral carcinogenesis, PI3K-Akt signaling pathway, Epstein-Barr virus infection
|
