SERPINC1

Gene Symbol SERPINC1
Entrez Gene 462
Alt Symbol AT3, AT3D, ATIII, THPH7
Species Human
Gene Type protein-coding
Description serpin peptidase inhibitor, clade C (antithrombin), member 1
Other Description antithrombin-III|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
Swissprots Q13815 B2R6P0 Q9UC78 P78439 P78447 P01008 Q5TC78 Q7KZ97 Q7KZ43
Accessions AAA19930 AAA51793 AAA51794 AAA51795 AAA51796 AAB19468 AAB23132 AAB40025 AAK60337 AAZ38825 BAC21173 BAC21174 BAC21175 BAC21176 CAA25059 CAA25060 CAA26951 CAA26952 CAA48690 CAI45858 CBX54631 EAW90969 EAW90970 EAW90971 P01008 AF130100 AAG35525 AK312654 BAG35537 BC022309 AAH22309 D29832 BAA06212 H62671 H65301 H71210 R84868 XM_005245198 XP_005245255 NM_000488 NP_000479
Function Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin. {ECO:0000269|PubMed:15853774}.
Subcellular Location Secreted, extracellular space.
Tissue Specificity Found in plasma.
Top Pathways Complement and coagulation cascades

Antithrombin III Human ELISA Kit - ab108801 from Abcam

Category ELISA Kit
Prices $489.00
Sizes 1 x 96 tests
Sensitivity = 3 ng/ml
Range 3.13 ng/ml - 200 ng/ml

Thrombin-Antithrombin Complex (TAT) Human ELISA Kit - ab108907 from Abcam

Category ELISA Kit
Prices $489.00
Sizes 1 x 96 tests
Sensitivity = 1.5 ng/ml
Range 1.48 ng/ml - 120 ng/ml
TAT measured in biological fluids, with background signal subtracted (duplicates +/- SD).

Mouse Antithrombin-III ELISA Kit (Sandwich ELISA) - LS-F6264 from LifeSpan Bioscience

Category ELISA Kit
Prices $740.00
Sizes 1 plate
Sensitivity 0.94 ng/ml
Range 0.94-60 ng/ml

Human Antithrombin-III ELISA Kit (Sandwich ELISA) - LS-F7926 from LifeSpan Bioscience

Category ELISA Kit
Prices $720.00
Sizes 1 plate
Sensitivity 1.38 ng/ml
Range 0.94-60 ng/ml

Human Antithrombin-III ELISA Kit (Sandwich ELISA) - LS-F10410 from LifeSpan Bioscience

Category ELISA Kit
Prices $590.00
Sizes 1 plate
Sensitivity 0.02 ng/ml
Range 0.94-60 ng/ml

Human Antithrombin-III ELISA Kit (Sandwich ELISA) - LS-F10838 from LifeSpan Bioscience

Category ELISA Kit
Prices $530.00
Sizes 1 plate
Sensitivity 15.6
Range 0.94-60 ng/ml

Human Serpin C1/Antithrombin-III Quantikine ELISA Kit - DSPC10 from R&D Systems

Category ELISA Kit
Prices $509.00
Sizes 1 kit
Sensitivity 0.097 ng/mL
Range 0.3 - 20 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine, Human Milk)
Human Serpin C1/Antithrombin-III Quantikine ELISA Kit

Quantikine Immunoassay Control Set 876 for Human Serpin C1 - QC208 from R&D Systems

Category ELISA Kit
Prices $125.00
Sizes 1 each

Antithrombin III Antibody Pair - 55R-ATIIIEIAKT from Fitzgerald

Category Antibody Pair
Prices $465.00
Sizes 5 plates

Murine Antithrombin III Antibody Pair - 55R-1017 from Fitzgerald

Category Antibody Pair
Prices $465.00
Sizes 4 plates

Antithrombin-III, SERPINC1, Human, ELISA Kit - E0878h from ARP American Research Products

Category ELISA Kit
Prices $476.00
Sizes 96 t
Range 15.6-1000 ng/mL

SERPINC1 (Human) ELISA kit - KA0456 from Acris Antibodies

Category ELISA Kit
Prices $650.00
Sizes 1 kit

SERPINC1 (Human) ELISA Kit - KA1836 from Acris Antibodies

Category ELISA Kit
Prices $650.00
Sizes 1 kit

Custom Human Antithrombin 3 ELISA - ELH-AT3 from RayBiotech

Category ELISA Kit
Prices $615.00, $1,107.00, $2,460.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Antithrombin (AT), ELISA Kit - MBS2024456 from MyBioSource

Category ELISA Kit
Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 0.41ng/mL.
Range 0.94-60ng/mL

Antithrombin (AT), ELISA Kit - MBS2024778 from MyBioSource

Category ELISA Kit
Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 1.38ng/mL.
Range 3.13-200ng/mL

Antithrombin (AT), ELISA Kit - MBS2024524 from MyBioSource

Category ELISA Kit
Prices $280.00, $390.00, $520.00, $2,100.00, $3,805.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 1.38ng/mL.
Range 31.25-2000ng/mL

Antithrombin III (AT III), ELISA Kit - MBS7221639 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/mL.

Antithrombin III (AT III), ELISA Kit - MBS7204089 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ug/mL.

Antithrombin III (AT3) - MBS733896 from MyBioSource

Category ELISA Kit

Antithrombin III (ATIII), ELISA Kit - MBS264513 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 5ng/ml.
Range 1000 ng/ml-15.6ng/ml

Antithrombin III (ATIII), ELISA Kit - MBS269637 from MyBioSource

Category ELISA Kit
Prices $290.00, $450.00, $1,755.00, $3,150.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.5 ng/ml.
Range 100 ng/ml-1.56 ng/ml

Antithrombin III (ATIII), ELISA Kit - MBS2600266 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Up to 0.05 ng/ml.

Antithrombin III (ATIII), ELISA Kit - MBS264843 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Antithrombin III (ATIII), ELISA Kit - MBS268748 from MyBioSource

Category ELISA Kit
Prices $275.00, $420.00, $1,615.00, $2,880.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.8 ng/ml.
Range 300 ng/ml-4.7 ng/ml
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