JAK1

Gene Symbol JAK1
Entrez Gene 3716
Alt Symbol JAK1A, JAK1B, JTK3
Species Human
Gene Type protein-coding
Description Janus kinase 1
Other Description tyrosine-protein kinase JAK1
Swissprots P23458 Q9UD26 Q59GQ2
Accessions CBG22571 EAX06547 EAX06548 P23458 AB209057 BAD92294 AB219242 BAE02826 AK128375 AK314257 BC009079 BC023604 AAH23604 BC062431 AAH62431 BC111401 AAI11402 BC132729 AAI32730 BX647675 BX648044 HQ628631 AER93381 M64174 AAA36527 XM_005270841 XP_005270898 XM_006710624 XP_006710687 XM_011541395 XP_011539697 NM_002227 NP_002218
Function Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. {ECO:0000269|PubMed:11909529}.
Subcellular Location Endomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated.
Tissue Specificity Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue. {ECO:0000269|PubMed:7896447}.
Top Pathways Viral carcinogenesis, Pancreatic cancer, Signaling pathways regulating pluripotency of stem cells, Osteoclast differentiation, Epstein-Barr virus infection

JAK1 overexpression lysate - LY400824 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

JAK1 293 Cell Lysate - 400786 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Jak1 Overexpression Lysate (Native) - NBL1-12093 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: JAK1 Lysate [NBL1-12093] - Western Blot experiments. Left-Control; Right -Over-expression Lysate for JAK1

JAK1 Over-expression Lysate Product - GWB-9D7AD5 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human JAK1 Knockdown Stable Cell Line - CSC-DC007849 from Creative biogene

Category Cell Line
Species Human
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