entB

Gene Symbol entB
Entrez Gene 946178
Alt Symbol ECK0588, JW0587, entG
Species Escherichia coli
Gene Type protein-coding
Description isochorismatase
Other Description -
Swissprots P0ADI4 P15048 Q2MBK6
Accessions AAC73696 NP_415127
Function Involved in the biosynthesis of the siderophore enterobactin (enterochelin), which is a macrocyclic trimeric lactone of N-(2,3-dihydroxybenzoyl)-serine. The serine trilactone serves as a scaffolding for the three catechol functionalities that provide hexadentate coordination for the tightly ligated iron(2+) atoms. EntB is a bifunctional protein that serves as an isochorismate lyase and an aryl carrier protein (ArCP). Catalyzes the conversion of isochorismate to 2,3-dihydro-2,3- dihydroxybenzoate (2,3-diDHB), the precursor of 2,3- dihydroxybenzoate (DHB). In the enterobactin assembly, EntB functions as an aryl carrier protein phosphopantetheinylated near the C terminus by EntD to yield holo-EntB, which is then acylated by EntE with 2,3-dihydroxybenzoyl-AMP to form DHB-holo-EntB. Then this product will serve in the formation of the amide bond between 2,3-dihydroxybenzoate (DHB) and L-serine. {ECO:0000269|PubMed:16567620, ECO:0000269|PubMed:16632253, ECO:0000269|PubMed:19699210, ECO:00002
Subcellular Location Cytoplasm {ECO:0000269|PubMed:10692387}.
Top Pathways Biosynthesis of siderophore group nonribosomal peptides

Recombinant Escherichia coli Isochorismatase(entB) - CSB-YP364981ENV CSB-EP364981ENV CSB-BP364981ENV CSB-MP364981ENV from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Escherichia coli

E.coli entG protein - orb246519 from Biorbyt

Category Protein
Prices $221.00, $366.00, $646.00, $1,071.00, $1,692.00
Sizes 10 μg, 50 μg, 200 μg, 500 μg, 1 mg
Species Escherichia coli

Isochorismatase (entB), Recombinant Protein - MBS1019667 from MyBioSource

Category Protein
Prices $1,040.00, $1,040.00, $1,270.00, $1,270.00, $1,615.00, $1,615.00, $2,075.00, $2,075.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Escherichia coli
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