POLR2C

Gene Symbol	POLR2C
Entrez Gene	5432
Alt Symbol	RPB3, RPB31, hRPB33, hsRPB3
Species	Human
Gene Type	protein-coding
Description	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Other Description	DNA-directed RNA polymerase II 33 kDa polypeptide|DNA-directed RNA polymerase II subunit C|DNA-directed RNA polymerase II subunit RPB3|RNA polymerase II subunit 3|RNA polymerase II subunit B3|RPB33
Swissprots	O15161 P19387
Accessions	AAC24309 EAW82926 EAW82927 EAW82929 EAW82930 P19387 AF008443 AAC14355 AJ224143 CAA11842 AJ224144 CAA11843 AK293112 BAF85801 AK295582 BAH12113 AK300124 BAH13217 BC000409 AAH00409 BC003159 AAH03159 BC028157 AAH28157 BI458170 CR542041 CAG46838 DQ891411 ABM82337 DQ894586 ABM85512 EU176305 ABW03756 J05448 AAA36586 XM_011523111 XP_011521413 NM_032940 NP_116558 NM_002694
Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:9852112}.
Top Pathways	Huntington's disease, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

POLR2C CRISPR/Cas9 KO Plasmid (h) - sc-410945 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

POLR2C HDR Plasmid (h) - sc-410945-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

POLR2C Double Nickase Plasmid (h) - sc-410945-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

POLR2C Double Nickase Plasmid (h2) - sc-410945-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

POLR2C CRISPR Activation Plasmid (h) - sc-410945-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

POLR2C CRISPR Activation Plasmid (h2) - sc-410945-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

POLR2C Lentiviral Activation Particles (h) - sc-410945-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

POLR2C Lentiviral Activation Particles (h2) - sc-410945-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

POLR2C siRNA (h) - sc-93093 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

POLR2C shRNA Plasmid (h) - sc-93093-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

POLR2C shRNA (h) Lentiviral Particles - sc-93093-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

POLR2C RNAi - H00005432-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

POLR2C RNAi - H00005432-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU084451 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17113 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17113 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR12339 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr12339

POLR2C siRNA (Human) - CRH3635 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human POLR2C (NM_032940.2) - SHH379400 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human POLR2C(NM_032940.2) - SHR127372 from Creative biogene Category siRNA Species Reactivities Human

Human POLR2C siRNA - orb264137 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

POLR2C shRNA Plasmid (Human) - CHH3635 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

POLR2C miRNA 3'UTR clone - MiUTR1H-08073 from Creative biogene Species Reactivities Human

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