Gene Symbol |
Stk10
|
Entrez Gene |
29398
|
Alt Symbol |
-
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
serine/threonine kinase 10
|
Other Description |
serine/threonine-protein kinase 10
|
Swissprots |
E9PTG8 D3ZUC0
|
Accessions |
E9PTG8 EDM04059 EDM04060 EDM04061 EDM04062 U33472 AAC52648 XM_008767561 XP_008765783 NM_019206 NP_062079
|
Function |
Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
|