NELFA

Gene Symbol NELFA
Entrez Gene 7469
Alt Symbol NELF-A, P/OKcl.15, WHSC2
Species Human
Gene Type protein-coding
Description negative elongation factor complex member A
Other Description negative elongation factor A|wolf-Hirschhorn syndrome candidate 2 protein
Swissprots A2A2T1 Q9H3P2 O95392
Accessions EAW82545 EAW82546 EAW82547 Q9H3P2 AB044549 BAB18651 AF101434 AAC72982 AF131751 AAD20034 AI218582 AI560345 AK001304 BAG50890 AK094040 BAG52802 AK095737 BAG53117 AK126056 BAG54283 AK222853 BAD96573 BC002764 AAH02764 DB082393 EU831413 ACE87100 EU831506 ACE86425 XM_006713916 XP_006713979 XM_011513561 XP_011511863 NM_005663 NP_005654
Function Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. Probably required to interact with the RNA polymerase II complex. {ECO:0000269|PubMed:10199401, ECO:0000269|PubMed:12563561, ECO:0000269|PubMed:12612062}.
Subcellular Location Nucleus {ECO:0000269|PubMed:11150502}.
Tissue Specificity Ubiquitous. Expressed in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas. Expressed at lower level in adult lung. Expressed in fetal brain, lung, liver and kidney. {ECO:0000269|PubMed:10409432, ECO:0000269|PubMed:11150502, ECO:0000269|PubMed:12612062}.

NELF-A CRISPR/Cas9 KO Plasmid (h) - sc-401058 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-A HDR Plasmid (h) - sc-401058-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-A Double Nickase Plasmid (h) - sc-401058-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-A Double Nickase Plasmid (h2) - sc-401058-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-A CRISPR Activation Plasmid (h) - sc-401058-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-A CRISPR Activation Plasmid (h2) - sc-401058-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-A Lentiviral Activation Particles (h) - sc-401058-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-A Lentiviral Activation Particles (h2) - sc-401058-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-A siRNA (h) - sc-38095 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NELF-A shRNA Plasmid (h) - sc-38095-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NELF-A shRNA (h) Lentiviral Particles - sc-38095-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

WHSC2 RNAi - H00007469-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU118561 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22897 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22897 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04301 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr04301

NELFA siRNA (Human) - CRH5109 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NELF-A CRISPR/Cas9 KO Plasmid (h2) - sc-401058-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NELF-A HDR Plasmid (h2) - sc-401058-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

shRNA set against Human WHSC2 (NM_005663.4) - SHH447000 from Creative biogene

Category siRNA
Species Reactivities Human

Human NELFA siRNA - orb265611 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NELFA shRNA Plasmid (Human) - CHH5109 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

WHSC2 miRNA 3'UTR clone - MiUTR3H-08153 from Creative biogene

Species Reactivities Human
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