| Gene Symbol |
Myo5b
|
| Entrez Gene |
25132
|
| Alt Symbol |
Myr6
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
myosin Vb
|
| Other Description |
Myosin of the dilute-myosin-V family|myosin 5B|myosin heavy chain myr 6|myosin-Vb|unconventional myosin-Vb
|
| Swissprots |
P70569
|
| Accessions |
EDL82886 EDL82887 EDL82888 P70569 U60416 AAB38840 XM_006254908 XP_006254970 XM_008772085 XP_008770307 XM_008772086 XP_008770308 NM_017083 NP_058779
|
| Function |
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis. {ECO:0000250|UniProtKB:Q9ULV0}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:1469047}.
|