ITGB2

Gene Symbol	ITGB2
Entrez Gene	3689
Alt Symbol	CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7
Species	Human
Gene Type	protein-coding
Description	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Other Description	cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor)|complement receptor C3 beta-subunit|integrin beta chain, beta 2|integrin beta-2|leukocyte cell adhesion molecule CD18|leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
Swissprots	D3DSM1 Q9UD72 Q53HS5 B3KTS8 Q16418 P05107
Accessions	AAD14951 AAD14952 AAL14027 AHZ44414 AHZ44415 AHZ44416 AHZ44417 AHZ44418 AHZ44419 AHZ44420 AHZ44421 AHZ44422 AHZ44423 AHZ44424 AHZ44425 AHZ44426 AHZ44427 AHZ44428 AHZ44429 AHZ44430 AHZ44431 AHZ44432 AHZ44433 AHZ44434 AHZ44435 AHZ44436 AHZ44437 AHZ44438 AHZ44439 CAA45427 CAB90553 EAX09381 EAX09382 EAX09383 EAX09384 EAX09385 P05107 AB208909 BAD92146 AK095992 BAG53190 AK097216 AK097864 AK128344 AK222505 BAD96225 AK303488 BAG64523 AU279404 BC005861 AAH05861 BC021077 AAH21077 CA447686 DA200537 DQ892684 ABM83610 DQ895927 ABM86853 EU832617 ACE87708 EU832689 ACE87021 L78790 AAL40068 M15395 AAA59490 S81234 AAB21404 Y00057 CAA68266 XM_006724001 XP_006724064 NM_000211 NP_000202 NM_001127491 NP_001120963 NM_001303238 NP_001290167
Function	Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha- D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. {ECO:0000269|PubMed:18587400}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Malaria, Legionellosis, Tuberculosis, Hippo signaling pathway, HTLV-I infection

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ITGB2 / CD18 ELISA Kit (Sandwich ELISA) - LS-F9874 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 0.129 ng/ml Range 0.313-20 ng/ml

Integrin beta-2 (ITGB2), Human, ELISA Kit - E01I0443 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 0.1ng/ml Range 1.0-25ng/ml

Integrin beta-2, ITGB2, Human, ELISA Kit - E0236h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t

ITGB2 (Human) Matched Antibody Pair - H00003689-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

Integrin Beta 2 (ITGb2), ELISA Kit - MBS2019445 from MyBioSource Category ELISA Kit Prices $355.00, $540.00, $730.00, $2,985.00, $5,410.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.129ng/mL. Range 0.313-20ng/mL

Integrin beta 2 (ITGB2), ELISA Kit - MBS7225757 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2, ELISA Kit - MBS281215 from MyBioSource Category ELISA Kit Prices $465.00, $790.00, $3,500.00, $6,655.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7208970 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7250800 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7239051 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7229085 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7242668 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7207086 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7208136 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7226085 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7250164 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Integrin beta-2 (ITGB2), ELISA Kit - MBS7230198 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) , ELISA Kit - MBS704374 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 3.9 pg/ml. Range 15.6 pg/ml-1000 pg/ml.

ELISA Kit for Integrin Beta 2 (ITGb2) - SEB586Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.119ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Human integrin β2,ITG β2/CD11+CD18 ELISA Kit - CSB-E10004h from Cusabio Category ELISA Kit Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Bovine ITGB2 / CD18 ELISA Kit (Custom ELISA) - LS-F14075 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Human ITGB2 / CD18 ELISA Kit (Custom ELISA) - LS-F14076 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Pig ITGB2 / CD18 ELISA Kit (Custom ELISA) - LS-F14077 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Mouse ITGB2 / CD18 ELISA Kit (Custom ELISA) - LS-F14078 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.313-20 ng/ml

Human ITGB2 / CD18 ELISA Kit (Sandwich ELISA) - LS-F21152 from LifeSpan Bioscience Category ELISA Kit Prices $590.00 Sizes 1 plate Sensitivity 0.094 ng/ml Range 0.313-20 ng/ml

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