| Gene Symbol | Lhx6 |
|---|---|
| Entrez Gene | 16874 |
| Alt Symbol | Lhx6.1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | LIM homeobox protein 6 |
| Other Description | LIM-homeodomain protein 6.1|LIM/homeobox protein Lhx6|LIM/homeobox protein Lhx6.1 |
| Swissprots | O88706 Q9R1R1 Q9R1R0 Q6P1H2 |
| Accessions | EDL08667 EDL08668 EDL08669 EDL08670 Q9R1R0 AB031039 BAA83420 AB031040 BAA83421 AJ000337 CAA04011 AK090339 BAC41175 AK140987 AK149585 BAE28976 BC065077 AAH65077 CO042780 XM_006497744 XP_006497807 XM_006497745 XP_006497808 XR_374064 NM_001083125 NP_001076594 NM_001083126 NP_001076595 NM_001083127 NP_001076596 NM_008500 NP_032526 |
| Function | Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. {ECO:0000269|PubMed:10393337, ECO:0000269|PubMed:15201337, ECO:0000269|PubMed:17376969, ECO:0000269|PubMed:18339674, ECO:0000269|PubMed:18613121}. |
| Subcellular Location | Nucleus {ECO:0000305}. |
| Tissue Specificity | Brain specific. Expressed by neurons in the amygdala that are activated by reproductive olfactory stimuli and project in regions of the hypothalamus involved in reproduction (at protein level). {ECO:0000269|PubMed:10393337, ECO:0000269|PubMed:15944132}. |
LHX6 CRISPR/Cas9 KO Plasmid (m) - sc-421429 from Santa Cruz Biotechnology
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LHX6 HDR Plasmid (m) - sc-421429-HDR from Santa Cruz Biotechnology
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LHX6 Double Nickase Plasmid (m) - sc-421429-NIC from Santa Cruz Biotechnology
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LHX6 Double Nickase Plasmid (m2) - sc-421429-NIC-2 from Santa Cruz Biotechnology
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LHX6 CRISPR Activation Plasmid (m) - sc-421429-ACT from Santa Cruz Biotechnology
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LHX6 CRISPR Activation Plasmid (m2) - sc-421429-ACT-2 from Santa Cruz Biotechnology
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LHX6 Lentiviral Activation Particles (m) - sc-421429-LAC from Santa Cruz Biotechnology
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LHX6 Lentiviral Activation Particles (m2) - sc-421429-LAC-2 from Santa Cruz Biotechnology
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LHX6 siRNA (m) - sc-75426 from Santa Cruz Biotechnology
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LHX6 shRNA Plasmid (m) - sc-75426-SH from Santa Cruz Biotechnology
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LHX6 shRNA (m) Lentiviral Particles - sc-75426-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU082161 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN34764 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34764 from Sigma-Aldrich
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LHX6 siRNA (Mouse) - CRM2344 from Cohesion Biosciences
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shRNA set against Mouse LHX6 (NM_008500.2) - SHH330159 from Creative biogene
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shRNA set against Mouse Lhx6(NM_001083127.1) - SHH148713 from Creative biogene
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shRNA set against Mouse Lhx6(NM_001083126.1) - SHH148735 from Creative biogene
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shRNA set against Mouse Lhx6(NM_001083127.1) - SHH148767 from Creative biogene
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shRNA set against Mouse Lhx6(NM_008500.2) - SHH148781 from Creative biogene
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shRNA set against Mouse Lhx6(NM_001083125.1) - SHH148799 from Creative biogene
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LHX6 shRNA Plasmid (Mouse) - CHM2344 from Cohesion Biosciences
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LHX6 miRNA 3'UTR clone - MiUTR1M-06628 from Creative biogene
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LHX6 miRNA 3'UTR clone - MiUTR1M-06629 from Creative biogene
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LHX6 miRNA 3'UTR clone - MiUTR1M-06630 from Creative biogene
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