| Gene Symbol |
GPI
|
| Entrez Gene |
100008744
|
| Alt Symbol |
-
|
| Species |
Rabbit
|
| Gene Type |
protein-coding
|
| Description |
glucose-6-phosphate isomerase
|
| Other Description |
AMF|NLK|PGI|PHI|autocrine motility factor|glucose phosphate isomerase|neuroleukin|phosphoglucose isomerase|phosphohexose isomerase
|
| Swissprots |
Q9N184 Q9N1E2
|
| Accessions |
Q9N1E2 AF199601 AAF13713 AF222069 AAF35988 GBCM01001145 NM_001082069 NP_001075538
|
| Function |
Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm. Secreted.
|
| Top Pathways |
Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Amino sugar and nucleotide sugar metabolism, Carbon metabolism, Starch and sucrose metabolism
|