Gene Symbol | PABPC5 |
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Entrez Gene | 140886 |
Alt Symbol | PABP5 |
Species | Human |
Gene Type | protein-coding |
Description | poly(A) binding protein, cytoplasmic 5 |
Other Description | polyadenylate-binding protein 5 |
Swissprots | Q5JQF4 A8K240 Q6P529 Q96DU9 Q9UFE5 |
Accessions | CAC42826 EAX02776 Q96DU9 AK290105 BAF82794 AK297327 BAG59787 AL122118 CAB59276 BC063113 AAH63113 HQ447581 ADQ32067 NM_080832 NP_543022 |
Function | Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Expressed in fetal brain and in a range of adult tissues. |
Top Pathways | RNA degradation, RNA transport, mRNA surveillance pathway |
PABPC5 CRISPR/Cas9 KO Plasmid (h) - sc-414505 from Santa Cruz Biotechnology
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PABPC5 HDR Plasmid (h) - sc-414505-HDR from Santa Cruz Biotechnology
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PABPC5 Double Nickase Plasmid (h) - sc-414505-NIC from Santa Cruz Biotechnology
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PABPC5 Double Nickase Plasmid (h2) - sc-414505-NIC-2 from Santa Cruz Biotechnology
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PABPC5 CRISPR Activation Plasmid (h) - sc-414505-ACT from Santa Cruz Biotechnology
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PABPC5 CRISPR Activation Plasmid (h2) - sc-414505-ACT-2 from Santa Cruz Biotechnology
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PABPC5 Lentiviral Activation Particles (h) - sc-414505-LAC from Santa Cruz Biotechnology
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PABPC5 Lentiviral Activation Particles (h2) - sc-414505-LAC-2 from Santa Cruz Biotechnology
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PABPC5 siRNA (h) - sc-91049 from Santa Cruz Biotechnology
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PABPC5 shRNA Plasmid (h) - sc-91049-SH from Santa Cruz Biotechnology
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PABPC5 shRNA (h) Lentiviral Particles - sc-91049-V from Santa Cruz Biotechnology
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PABPC5 RNAi - H00140886-R01 from Novus Biologicals
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MISSION® esiRNA - EHU155371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16254 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16254 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10579 from Sigma-Aldrich
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PABPC5 siRNA (Human) - CRJ5343 from Cohesion Biosciences
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shRNA set against Human PABPC5 (NM_080832.2) - SHH369804 from Creative biogene
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PABPC5 shRNA Plasmid (Human) - CHJ5343 from Cohesion Biosciences
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PABPC5 miRNA 3'UTR clone - MiUTR3H-02745 from Creative biogene
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