| Gene Symbol |
ZP3
|
| Entrez Gene |
7784
|
| Alt Symbol |
ZP3A, ZP3B, ZPC, Zp-3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zona pellucida glycoprotein 3 (sperm receptor)
|
| Other Description |
ZP3A/ZP3B|sperm receptor|zona pellucida glycoprotein 3A (sperm receptor)|zona pellucida glycoprotein 3B|zona pellucida glycoprotein ZP3|zona pellucida protein C|zona pellucida sperm-binding protein 3
|
| Swissprots |
Q06633 P21754 Q29RW0
|
| Accessions |
CAA01398 EAW71807 EAW71808 P21754 AK056788 AK292763 BAF85452 BC113949 AAI13950 BC140332 AAI40333 BC146482 AAI46483 BI828655 CA421411 DB328313 M60504 AAA61336 S52509 AAA13165 NM_001110354 NP_001103824 NM_007155 NP_009086
|
| Function |
The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
|
| Subcellular Location |
Processed zona pellucida sperm-binding protein 3: Secreted, extracellular space, extracellular matrix. Note=The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida.
|
| Tissue Specificity |
Oocytes.
|