DCTN1

Gene Symbol DCTN1
Entrez Gene 1639
Alt Symbol DAP-150, DP-150, P135
Species Human
Gene Type protein-coding
Description dynactin 1
Other Description 150 kDa dynein-associated polypeptide|dynactin 1 (p150, glued homolog, Drosophila)|dynactin subunit 1
Swissprots E9PGE1 O95296 Q9UIU2 G5E9H4 Q9UIU1 E9PFS5 B4DM45 A8MY36 Q9BRM9 Q14203 Q6IQ37
Accessions AAD03694 AAD55811 AAD55812 CCQ43248 EAW99684 EAW99685 EAW99686 EAW99687 Q14203 AB209625 BAD92862 AJ709213 AK055298 AK297286 BAG59757 AK314352 AK315014 BC006163 BC013978 BC071583 AAH71583 BT006758 AAP35404 BX640799 CAE45882 BX647925 CAH10575 BX647972 CAH10572 CA448857 DA111497 DA315227 DA417935 DC309469 EU831597 ACE87197 EU831684 ACE86518 U73799 AAB52575 U90445 AAD00701 X98801 CAA67333 NM_001135040 NP_001128512 NM_001135041 NP_001128513 NM_001190836 NP_001177765 NM_001190837 NP_001177766 NM_004082 NP_004073 NM_023019 NP_075408 NR_033935
Function Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein- dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17828277}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17828277}. Note=Colocalizes with microtubules.
Tissue Specificity Brain.
Top Pathways Huntington's disease, Vasopressin-regulated water reabsorption

Dynactin 1 (A-2) - sc-365274 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dynactin 1 (A-2): sc-365274. Western blot analysis of Dynactin 1 expression in Ramos (A), HeLa (B) and BC<sub>3</sub>H1 (C) whole cell lysates.

Dynactin 1 (B-4) - sc-365054 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dynactin 1 (B-4): sc-365054. Western blot analysis of Dynactin 1 expression in Ramos whole cell lysate.

Dynactin 1 (C-20) - sc-9801 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dynactin 1 (C-20): sc-9801. Immunoperoxidase staining of formalin fixed, paraffin-embedded human lower stomach tissue showing cytoplasmic staining of glandular cells.

Dynactin 1 (E-6) - sc-271166 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Dynactin 1 (E-6): sc-271166. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

Dynactin 1 (H-300) - sc-11363 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Dynactin 1 (H-300): sc-11363. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Dynactin p150 (G-18) - sc-9804 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Dynactin p150 (G-18): sc-9804. Immunoperoxidase staining of formalin fixed, paraffin-embedded human upper stomach tissue showing cytoplasmic staining of glandular cells.

Dynactin p150 (N-19) - sc-9803 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Dynactin p150 (12) - sc-135890 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/500 µl
Host Mouse
Clonality Monoclonal
Dynactin p150 (12): sc-135890. Western blot analysis of Dynactin 1 expression in non-transfected 293: sc-110760 (A), human Dynactin 1 transfected 293: sc-177152 (B) and HeLa (C) whole cell lysates.

Anti-DCTN1 antibody - ab75034 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-DCTN1 antibody (ab75034) at 1/500 dilutionLane 1 : rat brain lysateLane 2 : rat brain lysate plus immunising peptide

Anti-DCTN1 antibody - ab81057 from Abcam

Host Sheep
Clonality Polyclonal

Anti-DCTN1 antibody - ab96004 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-DCTN1 antibody (ab96004) at 1/3000 dilution + Jurkat whole cell lysate at 30 µg

Anti-DCTN1 antibody - ab54738 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-DCTN1 antibody (ab54738) at 1/500 dilution + recombinant DCTN1 at 0.2 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/5000 dilution

Anti-DCTN1 antibody [3D5-C6-D5] - ab151184 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D5-C6-D5
All lanes : Anti-DCTN1 antibody [3D5-C6-D5] (ab151184) at 1/1000 dilutionLane 1 : A2780 cell lysateLane 2 : TF-1 cell lysateLane 3 : HepG2 cell lysateLane 4 : MCF7 cell lysateLane 5 : A431 cell lysateLane 6 : 293T cell lysateLane 7 : K562 cell lysate

Anti-DCTN1 / Dynactin 1 Antibody (aa120-170) - LS-C94057 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-DCTN1 / Dynactin 1 Antibody (Internal) - LS-C94059 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Sheep
Clonality Polyclonal

Anti-DCTN1 / Dynactin 1 Antibody (aa1082-1270) - LS-C125500 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-DCTN1 / Dynactin 1 Antibody (N-Terminus) - LS-C144959 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DCTN1 / Dynactin 1 Antibody (aa1100-1150) - LS-C289771 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DCTN1 / Dynactin 1 Antibody (aa1228-1278) - LS-C289774 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DCTN1 / Dynactin 1 Antibody (aa967-1016) - LS-C151276 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
DCTN1 antibody Western Blot of Rat Thymus.

Anti-DCTN1 / Dynactin 1 Antibody - LS-C178264 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot detection of DCTN1 in A2780,TF-1,HepG2,MCF7,A431&K562 cell lysate(1:1000 diluted).

Anti-DCTN1 / Dynactin 1 Antibody (clone 1E12) - LS-C197028 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1E12
Detection limit for recombinant GST tagged DCTN1 is 0.1 ng/ml as a capture antibody.

Anti-DCTN1 / Dynactin 1 Antibody - LS-C192753 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of Jurkat cell lines, using DCTN1 antibody.

Anti-DCTN1 / Dynactin 1 Antibody - LS-C335182 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human esophageal cancer using DCTN1 antibody at dilution of 1:100 (200x lens).

Anti-DCTN1 / Dynactin 1 Antibody (aa1216-1278) IHC-plus™ - LS-B10901 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-DCTN1 / Dynactin 1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10901 concentration 5 ug/ml.
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