HSD17B3

Gene Symbol HSD17B3
Entrez Gene 3293
Alt Symbol EDH17B3, SDR12C2
Species Human
Gene Type protein-coding
Description hydroxysteroid (17-beta) dehydrogenase 3
Other Description 17-beta-HSD 3|17-beta-HSD3|17-beta-hydroxysteroid dehydrogenase type 3|short chain dehydrogenase/reductase family 12C member 2|short chain dehydrogenase/reductase family 12C, member 2|testicular 17-beta-hydroxysteroid dehydrogenase|testosterone 17-beta-dehydrogenase 3
Swissprots P37058 Q5U0Q6
Accessions AAP88937 CBH19319 EAW92645 P37058 BC034281 AAH34281 BT019371 AAV38178 CR541894 CAG46692 DQ891812 ABM82738 DQ894995 ABM85921 U05659 AAC50066 XM_005251970 XP_005252027 XM_006717095 XP_006717158 XM_011518618 XP_011516920 XM_011518619 XP_011516921 XM_011518620 XP_011516922 XM_011518621 XP_011516923 NM_000197 NP_000188
Function Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH.
Tissue Specificity Testis.
Top Pathways Steroid hormone biosynthesis

17β-HSD3 (C-14) - sc-66415 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
17β-HSD3 (C-14): sc-66415. Immunoperoxidase staining of formalin fixed, paraffin-embedded human hippocampus tissue showing cytoplasmic staining of neuronal cells.

Anti-HSD17B3 antibody - ab102771 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-HSD17B3 antibody (ab102771) at 1/100 dilution + K562 cell line lysates at 35 µg

Anti-HSD17B3 antibody - ab126228 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-HSD17B3 antibody (ab126228) at 1/500 dilution + Raji whole cell lysate at 30 µg

Anti-HSD17B3 antibody - ab70089 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-HSD17B3 antibody (ab70089) at 1/500 dilutionLane 1 : HSD17B3 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-HSD17B3 Antibody (aa89-118, AP) - LS-C215180 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B3 Antibody (aa89-118, APC) - LS-C215181 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B3 Antibody (aa89-118, Biotin) - LS-C215182 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B3 Antibody (aa89-118, FITC) - LS-C215183 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B3 Antibody (aa89-118, Azide-free, HRP) - LS-C215184 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B3 Antibody (aa89-118, PE) - LS-C215185 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B3 Antibody (aa51-100) - LS-C146038 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HSD17B3 antibody LS-C146038 Western blot of 721_B Cell lysate. Antibody concentration 1 ug/ml.

Anti-HSD17B3 Antibody - LS-C308324 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-HSD17B3 Antibody - LS-C311233 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-HSD17B3 Antibody (aa96-126) - LS-C322106 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HSD17B3 Antibody (aa89-118) - LS-C165035 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human testis tissue reacted with HSD17B3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

HSD17B3 Antibody - NBP2-16884 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HSD17B3 Antibody - NBP1-80776 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HSD17B3 Antibody [NBP1-80776] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY424871)

HSD17B3 Antibody - H00003293-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: HSD17B3 Antibody [H00003293-A01] - D17B3 polyclonal antibody (A01), Lot # 060614JCS1. Western Blot analysis of HSD17B3 expression in Raw 264.7.

HSD17B3 Antibody - NBP2-38807 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: HSD17B3 Antibody [NBP2-38807] - Staining of human testis shows moderate cytoplasmic positivity in Leydig cells.

HSD17B3 Antibody - H00003293-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: HSD17B3 Antibody [H00003293-D01P] - Analysis of HSD17B3 expression in transfected 293T cell line by HSD17B3 polyclonal antibody.Lane 1: HSD17B3 transfected lysate(34.50 KDa).Lane 2: Non-transfected lysate.

HSD17B3 Antibody - H00003293-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: HSD17B3 Antibody [H00003293-B01P] - Analysis of HSD17B3 expression in transfected 293T cell line by HSD17B3 polyclonal antibody. Lane1:HSD17B3 transfected lysate(34.1 KDa). Lane2:Non-transfected lysate.

Rabbit Anti-HSD17B3 Polyclonal Antibody - bs-3905R from Bioss

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat brain labeled with Anti-HSD17B3 Polyclonal Antibody, Unconjugated (bs-3905R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

Anti-HSD17B3 antibody produced in rabbit - SAB1401188 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-HSD17B3, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401188</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~34.50 kDa using HSD17B3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-HSD17B3 antibody produced in rabbit - HPA015307 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HSD17B3: <B>Cat. No. HPA015307</B>: Immunohistochemical staining of human testis shows cytoplasmic positivity of cells in seminiferus ducts.

Anti-HSD17B3 antibody produced in mouse - SAB1405969 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HSD17B3: <B>Cat. No. SAB1405969</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~34.1 kDa using HSD17B3 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.
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