| Gene Symbol |
VTI1B
|
| Entrez Gene |
10490
|
| Alt Symbol |
VTI1, VTI1-LIKE, VTI1L, VTI2, v-SNARE, vti1-rp1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vesicle transport through interaction with t-SNAREs 1B
|
| Other Description |
vesicle transport through interaction with t-SNAREs homolog 1B|vesicle transport v-SNARE protein Vti1-like 1|vesicle-associated soluble NSF attachment protein receptor
|
| Swissprots |
Q9UEU0 Q96J28 O43547
|
| Accessions |
EAW80945 EAW80946 EAW80947 Q9UEU0 AF035824 AAC52016 AF060902 AAC73059 AK291689 BAF84378 AK310839 AK316572 BAG38161 BC003142 AAH03142 BC042390 BI597967 BT019348 AAV38155 BT019960 AAV38763 CR456757 CAG33038 CR542095 CAG46892 NM_006370 NP_006361
|
| Function |
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
|
| Subcellular Location |
Late endosome membrane {ECO:0000269|PubMed:23217709}; Single-pass type IV membrane protein {ECO:0000269|PubMed:23217709}. Lysosome membrane {ECO:0000269|PubMed:23217709}. Cytoplasmic granule {ECO:0000269|PubMed:23217709}.
|
| Tissue Specificity |
Expressed in all tissues examined.
|
| Top Pathways |
SNARE interactions in vesicular transport
|
![Western Blot: VTI1B Overexpression Lysate (Adult Normal) [NBL1-17769] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VTI1B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/2734_VTI1B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17769-img0002.jpg)