TMPRSS6

Gene Symbol	TMPRSS6
Entrez Gene	164656
Alt Symbol	IRIDA
Species	Human
Gene Type	protein-coding
Description	transmembrane protease, serine 6
Other Description	matriptase-2|membrane-bound mosaic serine proteinase matriptase-2|transmembrane protease serine 6|type II transmembrane serine protease 6
Swissprots	Q8IUE2 Q6UXD8 Q6ICC2 B0QYB4 B0QYB7 B0QYB8 Q8IU80 Q8IXV8 Q5TI06
Accessions	AAL16413 EAW60141 EAW60142 EAW60143 Q8IU80 AJ319876 CAC85953 AW295507 AY055384 AAL16414 AY358398 AAQ88764 BC039082 AAH39082 CR456446 CAG30332 CU013044 CAK54475 CU013332 CAK54774 XM_006724162 XP_006724225 XM_006724163 XP_006724226 XM_011529987 XP_011528289 XM_011529988 XP_011528290 XM_011529989 XP_011528291 NM_001289000 NP_001275929 NM_001289001 NP_001275930 NM_153609 NP_705837
Function	Serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. Can also activate urokinase-type plasminogen activator with low efficiency. May play a specialized role in matrix remodeling processes in liver. Plays a role in the regulation of iron homeostasis, a process involving HAMP. Required to sense iron deficiency and suppress activation of the HAMP promoter. {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:18408718}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:20518742}; Single-pass type II membrane protein {ECO:0000269|PubMed:12149247, ECO:0000269|PubMed:20518742}.
Tissue Specificity	Liver specific. {ECO:0000269|PubMed:12149247}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TMPRSS6 ELISA Kit (Sandwich ELISA) - LS-F8729 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.27 ng/ml Range 0.781-50 ng/ml

Transmembrane protease serine 6 (TMPRSS6), Human, ELISA Kit - CSB-EL023928HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Transmembrane Protease, Serine 6 (TMPRSS6), Human, ELISA Kit - SEF817Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.35ng/mL Range 0.78 -50ng/mL

Transmembrane Protease, Serine 6, ELISA Kit - MBS102455 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transmembrane Protease, Serine 6, ELISA Kit - MBS070014 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transmembrane Protease, Serine 6, ELISA Kit - MBS064414 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/ml. Range 3.12 ng/ml - 100 ng/ml.

Transmembrane Protease, Serine 6, ELISA Kit - MBS103604 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transmembrane Protease, Serine 6, ELISA Kit - MBS067526 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Transmembrane Protease, Serine 6, ELISA Kit - MBS103905 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

transmembrane protease, serine 6, ELISA Kit - MBS706282 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human TMPRSS6 is typically less than 0.039 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 0.156 ng/ml -10 ng/ml.

Transmembrane Protease, Serine 6 (TMPRSS6), ELISA Kit - MBS2022582 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of TMPRSS6 is typically less than 0.27ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.78 -50ng/mL

Human TMPRSS6(Transmembrane Protease, Serine 6) ELISA Kit - E-EL-H5545 from Elabscience Category ELISA Kit Sensitivity 0.19 ng/mL Range 0.31—20 ng/mL

ELISA Kit for Transmembrane Protease, Serine 6 (TMPRSS6) - SEF817Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.35ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Human Transmembrane protease serine 6(TMPRSS6) ELISA kit - CSB-EL023928HU from Cusabio Category ELISA Kit Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

ELISA Kit for Transmembrane Protease, Serine 6 (TMPRSS6) - SEF817Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.35ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA's were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Transmembrane Protease, Serine 6, ELISA Kit - MBS059429 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 0.25ng/ml-8ng/ml.

Human Transmembrane Protease, Serine 6 (TMPRSS6) ELISA Kit - EKU07857 from Biomatik Category ELISA Kit Prices $735.00, $3,234.00, $5,880.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.27 ng/mL Range 0.781-50 ng/mL

Human TMPRSS6 ELISA Kit - abx153318 from Abbexa Category ELISA Kit Sensitivity 0.35 ng/ml Range 0.781 ng/ml - 50 ng/ml

ELISA Kit for Transmembrane Protease, Serine 6 (TMPRSS6) - SEF817Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.31ng/mL. Range 0.781-50ng/mL The standard curve concentrations used for the ELISA’s were 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL, 0.781ng/mL

Transmembrane Protease,Serine 6 (TMPRSS6), Human, ELISA Kit - DL-TMPRSS6-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.78 -50 ng/mL

Human TMPRSS6 ELISA Kit - abx573612 from Abbexa Category ELISA Kit Sensitivity 0.35 ng/ml Range 0.781 ng/ml - 50 ng/ml

Human Transmembrane protease serine 6 (TMPRSS6) ELISA Kit - EKC35867 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

TMPRSS6 - EKH8018 from Nordic BioSite Sensitivity 75pg/ml Range 125-8000pg/ml

Human TMPRSS6 ELISA Kit - E038454 from Biobool Category ELISA Kit Sensitivity < 75pg/ml

TMPRSS6 ELISA Kit (Human) (OKCD01883) - OKCD01883 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.27 ng/mL Range 0.781 - 50 ng/mL

Search more