| Gene Symbol |
Dao
|
| Entrez Gene |
114027
|
| Alt Symbol |
Dao1
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
D-amino-acid oxidase
|
| Other Description |
D-amino acid oxidase 1|DAAO|DAMOX
|
| Swissprots |
O35078
|
| Accessions |
EDM13954 EDM13955 EDM13956 EDM13957 O35078 AB003400 BAA22840 BC088395 AAH88395 NM_053626 NP_446078
|
| Function |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
|
| Subcellular Location |
Peroxisome.
|
| Top Pathways |
Glycine, serine and threonine metabolism, Peroxisome, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism
|