CSRP3

Gene Symbol CSRP3
Entrez Gene 8048
Alt Symbol CLP, CMD1M, CMH12, CRP3, LMO4, MLP
Species Human
Gene Type protein-coding
Description cysteine and glycine-rich protein 3 (cardiac LIM protein)
Other Description LIM domain only 4|cardiac LIM domain protein|cysteine and glycine-rich protein 3|muscle lim protein isoform
Swissprots Q9P131 P50461
Accessions AAD00189 ABN05285 CAC60376 EAW68355 EAW68356 P50461 AA192614 AF121260 AAF28868 AI184002 AJ711422 AK313289 BAG36097 BC005900 AAH05900 BC024010 AAH24010 BC057221 AAH57221 BF671742 DQ893125 ABM84051 DQ896402 ABM87401 JN898958 AFH66949 U20324 AAA91104 U49837 AAA92571 U72899 AAD00183 NM_003476 NP_003467
Function Positive regulator of myogenesis. Plays a crucial and specific role in the organization of cytosolic structures in cardiomyocytes. Could play a role in mechanical stretch sensing. May be a scaffold protein that promotes the assembly of interacting proteins at Z-line structures. It is essential for calcineurin anchorage to the Z line. Required for stress-induced calcineurin-NFAT activation (By similarity). {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000305}. Cytoplasm {ECO:0000269|PubMed:18505755}. Cytoplasm, cytoskeleton {ECO:0000305}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Mainly cytoplasmic (By similarity). In the nucleus it associates with the actin cytoskeleton (Potential). In the Z line, found associated with GLRX3 (By similarity). {ECO:0000250, ECO:0000305}.
Tissue Specificity Cardiac and slow-twitch skeletal muscles.

CRP3 CRISPR/Cas9 KO Plasmid (h) - sc-402025 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRP3 HDR Plasmid (h) - sc-402025-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRP3 Double Nickase Plasmid (h) - sc-402025-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRP3 Double Nickase Plasmid (h2) - sc-402025-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRP3 CRISPR Activation Plasmid (h) - sc-402025-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRP3 CRISPR Activation Plasmid (h2) - sc-402025-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRP3 Lentiviral Activation Particles (h) - sc-402025-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRP3 Lentiviral Activation Particles (h2) - sc-402025-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRP3 siRNA (h) - sc-106928 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRP3 shRNA Plasmid (h) - sc-106928-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRP3 shRNA (h) Lentiviral Particles - sc-106928-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CSRP3 RNAi - H00008048-R01V from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human
Western Blot: CSRP3 RNAi [H00008048-R01V] - Analysis of CSRP3 over-expressed 293 cell line, cotransfected with CSRP3 Validated Chimera RNAi or non-transfected control. Blot probed with H00008048-M03. GAPDH (36.1 kDa) used as loading control.

MISSION® esiRNA - EHU143361 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6668 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6668 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05645 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05645

CSRP3 siRNA (Human) - CRH5352 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CSRP3 RNAi - H00008048-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CSRP3 - MBS8225550 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CSRP3 (NM_003476.4) - SHH270681 from Creative biogene

Category siRNA
Species Reactivities Human

Human CSRP3 siRNA - orb265854 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CSRP3 shRNA Plasmid (Human) - CHH5352 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CSRP3 miRNA 3'UTR clone - MiUTR3H-03659 from Creative biogene

Species Reactivities Human
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