C4BPA

Gene Symbol C4BPA
Entrez Gene 722
Alt Symbol C4BP, PRP
Species Human
Gene Type protein-coding
Description complement component 4 binding protein, alpha
Other Description C4b-binding protein alpha chain|proline-rich protein
Swissprots Q5VVQ8 P04003
Accessions AAA36506 CAA27839 CAB51244 EAW93500 EAW93501 EAW93502 EAW93503 P04003 AK303793 BAG64750 AK303798 BAG64753 AK313164 BAG35982 BC022312 AAH22312 BQ019292 DQ892021 ABM82947 DQ895213 ABM86139 M31452 AAA36507 X02865 CAA26617 X07853 CAA30701 XM_005273251 XP_005273308 XM_005273252 XP_005273309 NM_000715 NP_000706
Function Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component.
Subcellular Location Secreted.
Tissue Specificity Chylomicrons in the plasma.
Top Pathways Complement and coagulation cascades, Pertussis

C4BPα CRISPR/Cas9 KO Plasmid (h) - sc-404684 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C4BPα HDR Plasmid (h) - sc-404684-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C4BPα Double Nickase Plasmid (h) - sc-404684-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C4BPα Double Nickase Plasmid (h2) - sc-404684-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C4BPα CRISPR Activation Plasmid (h) - sc-404684-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C4BPα CRISPR Activation Plasmid (h2) - sc-404684-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C4BPα Lentiviral Activation Particles (h) - sc-404684-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C4BPα Lentiviral Activation Particles (h2) - sc-404684-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C4BPα siRNA (h) - sc-42739 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C4BPα shRNA Plasmid (h) - sc-42739-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C4BPα shRNA (h) Lentiviral Particles - sc-42739-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU144071 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4930 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4930 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01655 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01655

C4BPA siRNA (Human) - CRH0501 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

C4BPA - MBS8222444 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C4BPA (NM_000715.3) - SHH251813 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human C4BPA(NM_000715.3) - SHG125587 from Creative biogene

Category siRNA
Species Reactivities Human

Human C4BPA siRNA - orb261003 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

C4BPA shRNA Plasmid (Human) - CHH0501 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

C4BPA miRNA 3'UTR clone - MiUTR1H-01402 from Creative biogene

Species Reactivities Human
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