| Gene Symbol |
Tubb3
|
| Entrez Gene |
22152
|
| Alt Symbol |
3200002H15Rik, M(beta)3, M(beta)6
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
tubulin, beta 3 class III
|
| Other Description |
betaIII-tubulin|tubulin beta-3 chain
|
| Swissprots |
Q3UF42 Q5I036 Q9ERD7
|
| Accessions |
BAJ07155 BAJ07156 BAJ07157 BAJ07158 EDL11742 Q9ERD7 AF312873 AAG26010 AK012528 BAB28299 AK014302 BAB29257 AK051298 BAC34596 AK082942 AK149014 BAE28719 BC031357 AAH31357 BC088749 AAH88749 NM_023279 NP_075768
|
| Function |
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. {ECO:0000269|PubMed:20074521}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton.
|
| Top Pathways |
Gap junction, Phagosome
|