RFC1

Gene Symbol RFC1
Entrez Gene 5981
Alt Symbol A1, MHCBFB, PO-GA, RECC1, RFC, RFC140
Species Human
Gene Type protein-coding
Description replication factor C (activator 1) 1, 145kDa
Other Description A1 140 kDa subunit|DNA-binding protein PO-GA|MHC binding factor, beta|RF-C 140 kDa subunit|activator 1 140 kDa subunit|activator 1 large subunit|activator 1 subunit 1|replication factor C 140 kDa subunit|replication factor C large subunit|replication factor C subunit 1|replication factor C1
Swissprots Q6PKU0 A8K6E7 Q86V46 Q5XKF5 P35251 Q86V41
Accessions AAS94325 EAW92922 EAW92923 EAW92924 P35251 AF040250 AAB99788 AJ564999 CAD92367 AK291612 BAF84301 BC010387 BC035297 AAH35297 BC051751 AAH51751 BC051786 AAH51786 DA336360 EU447003 ABZ92532 L23320 AAA16121 L24783 X69821 CAA49475 XM_011513730 XP_011512032 XM_011513731 XP_011512033 NM_001204747 NP_001191676 NM_002913 NP_002904
Function The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins PCNA and activator 1. This subunit binds to the primer-template junction. Binds the PO-B transcription element as well as other GA rich DNA sequences. Could play a role in DNA transcription regulation as well as DNA replication and/or repair. Can bind single- or double-stranded DNA. {ECO:0000269|PubMed:8999859}.
Subcellular Location Nucleus.
Tissue Specificity Wide tissue distribution. Undetectable in placental tissue.
Top Pathways DNA replication, Mismatch repair, Nucleotide excision repair

RFC1 (B-5) - sc-271656 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
RFC1 (B-5): sc-271656. Western blot analysis of RFC1 expression in HeLa nuclear extract.

RFC1 (C-15) - sc-21878 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RFC1 (H-300) - sc-20993 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RFC1 (H-300): sc-20993. Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing nuclear staining of surface epithelial cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Anti-RFC1 antibody - ab3566 from Abcam

Prices $384.00
Sizes 50 µl
Host Goat
Clonality Polyclonal
ab3566, at a 1/500 dilution, staining Human RFC1 in HeLa cells. Cells were paraformaldehyde fixed (4% for 10min) and counter-stained with DAPI in order to show the nucleus. Please read abreview for more information.See Abreview

Anti-RFC1 antibody - ab180613 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of rat lung tissue labelling RFC1 with ab180613 at 1/200. Magnification: 400x.

Anti-RFC1 antibody - ab3853 from Abcam

Prices $378.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Detection of Human RFC 1 by Western Blot and Immunoprecipitation using Affinity Purified Rabbit anti-RFC 1 (ab3853)Sample: Nuclear Extract (NE, amounts used are indicated) from HeLa cells.Antibody: Affinity Purified Rb anti-RFC 1 (ab3853).WB - 0.5µg/ml, IP - 2µg/mg NE.Detection: ECL, 30 seconds

Anti-RFC1 antibody - ab94953 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RFC1 antibody (ab94953) at 1/500 dilution + H460 nuclear lysate

Anti-RFC1 antibody - ab57860 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57860 RFC1 antibody at 1ug/ml.

Anti-RFC1 antibody - ab195625 from Abcam

Prices $359.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
Anti-RFC1 antibody (ab195625) at 1/500 dilution + H460 nuclear lysate

Anti-RFC1 antibody - N-terminal - ab190944 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-RFC1 antibody - N-terminal (ab190944) at 0.5 µg/mlLane 1 : HeLa cell lysateLane 2 : SMMC cell lysateLane 3 : Jurkat cell lysateLane 4 : CEM cell lysateLane 5 : 293T cell lysate

Anti-RFC1 antibody - N-terminal - ab138857 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RFC1 antibody - N-terminal (ab138857) at 1/100 dilution + Human uterus cell line lysate at 35 µg

Anti-RFC1 / RFC Antibody - LS-C90971 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RFC1 / RFC Antibody - LS-C90972 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-RFC1 / RFC Antibody (aa26-54, AP) - LS-C268087 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RFC1 / RFC Antibody (aa26-54, Biotin) - LS-C268089 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RFC1 / RFC Antibody (aa26-54, APC) - LS-C268088 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RFC1 / RFC Antibody (aa26-54, Azide-free, HRP) - LS-C268090 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RFC1 / RFC Antibody (aa26-54, FITC) - LS-C268091 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RFC1 / RFC Antibody (aa26-54, PE) - LS-C268093 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RFC1 / RFC Antibody (aa26-54) - LS-C324623 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RFC1 / RFC Antibody (aa935-984) - LS-C117272 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
RFC1 antibody LS-C117272 Western blot of Fetal Heart lysate.

Anti-RFC1 / RFC Antibody (clone 3F8) - LS-C198080 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3F8
Detection limit for recombinant GST tagged RFC1 is approximately 0.3 ng/ml as a capture antibody.

Anti-RFC1 / RFC Antibody - LS-C137270 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-RFC1 / RFC Antibody (aa46-64) - LS-C312865 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of RFC1 / RFC antibody. Lane 1: HELA Cell Lysate. Lane 2: SMMC Cell Lysate. Lane 3: JURKAT Cell Lysate. Lane 4: CEM Cell Lysate. Lane 5: 293T Cell Lysate.

Anti-RFC1 / RFC Antibody - LS-C192892 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of MCF-7 cell lines, using RFC1 antibody.
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