| Gene Symbol |
CERK1
|
| Entrez Gene |
821717
|
| Alt Symbol |
LYSM DOMAIN RECEPTOR-LIKE KINASE 1, LYSM RLK1, chitin elicitor receptor kinase 1
|
| Species |
Arabidopsis thaliana
|
| Gene Type |
protein-coding
|
| Description |
chitin elicitor receptor kinase 1
|
| Other Description |
-
|
| Swissprots |
Q9LVE3 A8R7E6
|
| Accessions |
A8R7E6 AEE76532 AB367524 BAF92788 NM_113058 NP_566689
|
| Function |
Lysin motif (LysM) receptor kinase that functions as a cell surface receptor in chitin elicitor (chitooligosaccharides) signaling leading to innate immunity toward both biotic and abiotic stresses (e.g. tolerance to salinity, heavy-metal stresses, and Botrytis cinerea infection). Recognizes microbe- derived N-acetylglucosamine (NAG)-containing ligands. Involved in the resistance to pathogenic fungi Alternaria brassicicola and Erysiphe cichoracearum, probably by sensing microbe-associated molecular patterns (MAMP) and pathogen-associated molecular patterns (PAMP). Plays an essential role in detecting peptidoglycans (e.g. PGNs) and restricting bacterial growth. Target of the bacterial type III effector E3-ligase protein hopAB2/avrPtoB of Pseudomonas syringae pv. tomato DC3000 that mediates ubiquitination and subsequent proteolysis, thus blocking all defense responses by suppressing PAMP-triggered immunity (PTI). {ECO:0000269|PubMed:18042724, ECO:0000269|PubMed:18263776, ECO:0000269|PubMe
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:18042724}; Single-pass membrane protein {ECO:0000269|PubMed:18042724}.
|
| Tissue Specificity |
Expressed ubiquitously, with lowest expression in pollen. {ECO:0000269|PubMed:18263776}.
|
| Top Pathways |
Plant-pathogen interaction
|