HTR1E

Gene Symbol HTR1E
Entrez Gene 3354
Alt Symbol 5-HT1E
Species Human
Gene Type protein-coding
Description 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
Other Description 5-HT-1E|5-hydroxytryptamine receptor 1E|S31|serotonin receptor 1E
Swissprots E1P503 P28566 Q9P1Y1
Accessions AAA58355 BAA94458 CAA77558 EAW48616 EAW48617 P28566 AF498980 AAM21127 AL521170 BC069751 AAH69751 M91467 AAA58353 XM_011535789 XP_011534091 XM_011535790 XP_011534092 NM_000865 NP_000856
Function G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. {ECO:0000269|PubMed:14744596, ECO:0000269|PubMed:1513320, ECO:0000269|PubMed:1608964, ECO:0000269|PubMed:1733778, ECO:0000269|PubMed:21422162}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:14744596, ECO:0000269|PubMed:1513320, ECO:0000269|PubMed:1608964, ECO:0000269|PubMed:1733778, ECO:0000269|PubMed:21422162}; Multi- pass membrane protein {ECO:0000269|PubMed:14744596, ECO:0000269|PubMed:1513320, ECO:0000269|PubMed:1608964, ECO:0000269|PubMed:1733778, ECO:0000269|PubMed:21422162}.
Tissue Specificity Detected in brain. {ECO:0000269|PubMed:14744596}.
Top Pathways cAMP signaling pathway, Neuroactive ligand-receptor interaction

SR-1E CRISPR/Cas9 KO Plasmid (h) - sc-406988 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1E HDR Plasmid (h) - sc-406988-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1E Double Nickase Plasmid (h) - sc-406988-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1E Double Nickase Plasmid (h2) - sc-406988-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1E CRISPR Activation Plasmid (h) - sc-406988-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1E CRISPR Activation Plasmid (h2) - sc-406988-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1E Lentiviral Activation Particles (h) - sc-406988-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1E Lentiviral Activation Particles (h2) - sc-406988-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SR-1E siRNA (h) - sc-42227 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SR-1E shRNA Plasmid (h) - sc-42227-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SR-1E shRNA (h) Lentiviral Particles - sc-42227-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

5-HT1E RNAi - H00003354-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN10393 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10393 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

HTR1E siRNA (Human) - CRH2284 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HTR1E - MBS8200207 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HTR1E (NM_000865.2) - SHH315897 from Creative biogene

Category siRNA
Species Reactivities Human

HTR1E shRNA Plasmid (Human) - CHH2284 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HTR1E miRNA 3'UTR clone - MiUTR4H-TG04359 from Creative biogene

Species Reactivities Human
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