IGSF5

Gene Symbol IGSF5
Entrez Gene 150084
Alt Symbol GSF5, JAM4
Species Human
Gene Type protein-coding
Description immunoglobulin superfamily, member 5
Other Description JAM-4|immunoglobulin superfamily 5 like|immunoglobulin superfamily member 5|junctional adhesion molecule 4
Swissprots Q9NSI5
Accessions CAB90447 CCQ43066 Q9NSI5 AK092516 BAG52565 BC114922 BC156232 AAI56233 BC157006 AAI57007 HG511824 HG511825 HG511826 XM_011529472 XP_011527774 XM_011529473 XP_011527775 NM_001080444 NP_001073913
Function Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia- spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells- Sertoli cells (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Cell junction, tight junction {ECO:0000250}.
Top Pathways Tight junction, Epithelial cell signaling in Helicobacter pylori infection

Panoply™ Human IGSF5 Knockdown Stable Cell Line - CSC-DC007511 from Creative biogene

Category Cell Line
Species Human
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