Gene Symbol | TBC1D10A |
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Entrez Gene | 83874 |
Alt Symbol | EPI64, TBC1D10, dJ130H16.1, dJ130H16.2 |
Species | Human |
Gene Type | protein-coding |
Description | TBC1 domain family, member 10A |
Other Description | EBP50-PDX interactor of 64 kDa|EBP50-PDZ interactor of 64 kD|TBC1 domain family member 10A|rab27A-GAP-alpha |
Swissprots | O76053 Q20WK7 Q9BXI6 B3KXT8 Q543A2 |
Accessions | AAC23434 CAF86715 EAW59871 EAW59872 EAW59873 EAW59874 EAW59875 EAW59876 EAW59877 Q9BXI6 AB449894 BAH16637 AF331038 AAK35048 AK074656 BAC11117 AK093231 BAG52675 AK127939 BAG54600 AK131086 BAC85136 AK309455 BC022201 BC136815 AAI36816 BC142940 AAI42941 BC143051 AAI43052 BC143052 AAI43053 BC150187 AAI50188 BC150214 AAI50215 BC171775 AAI71775 CT841514 CAJ86444 DA944522 NM_001204240 NP_001191169 NM_031937 NP_114143 |
Function | Acts as GTPase-activating protein for RAB27A, but not for RAB2A, RAB3A, nor RAB4A. {ECO:0000269|PubMed:16923811}. |
Subcellular Location | Cell projection, microvillus {ECO:0000269|PubMed:16923811}. Note=Localizes to the microvilli- rich region of the syncytiotrophoblast. In melanocytes, located at the periphery of cells. |
EPI64 CRISPR/Cas9 KO Plasmid (h) - sc-407095 from Santa Cruz Biotechnology
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EPI64 HDR Plasmid (h) - sc-407095-HDR from Santa Cruz Biotechnology
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EPI64 Double Nickase Plasmid (h) - sc-407095-NIC from Santa Cruz Biotechnology
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EPI64 Double Nickase Plasmid (h2) - sc-407095-NIC-2 from Santa Cruz Biotechnology
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EPI64 CRISPR Activation Plasmid (h) - sc-407095-ACT from Santa Cruz Biotechnology
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EPI64 CRISPR Activation Plasmid (h2) - sc-407095-ACT-2 from Santa Cruz Biotechnology
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EPI64 Lentiviral Activation Particles (h) - sc-407095-LAC from Santa Cruz Biotechnology
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EPI64 Lentiviral Activation Particles (h2) - sc-407095-LAC-2 from Santa Cruz Biotechnology
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EPI64 siRNA (h) - sc-42520 from Santa Cruz Biotechnology
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EPI64 shRNA Plasmid (h) - sc-42520-SH from Santa Cruz Biotechnology
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EPI64 shRNA (h) Lentiviral Particles - sc-42520-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU153941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21046 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21046 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03536 from Sigma-Aldrich
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TBC1D10A siRNA (Human) - CRJ3215 from Cohesion Biosciences
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TBC1D10A - MBS8240782 from MyBioSource
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shRNA set against Human TBC1D10A (NM_031937.2) - SHH423724 from Creative biogene
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EPI64 CRISPR/Cas9 KO Plasmid (h2) - sc-407095-KO-2 from Santa Cruz Biotechnology
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EPI64 HDR Plasmid (h2) - sc-407095-HDR-2 from Santa Cruz Biotechnology
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TBC1D10A shRNA Plasmid (Human) - CHJ3215 from Cohesion Biosciences
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TBC1D10A miRNA 3'UTR clone - MiUTR3H-10971 from Creative biogene
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