Abca3

Gene Symbol Abca3
Entrez Gene 27410
Alt Symbol 1810036E22Rik, ABC-C, Abc3
Species Mouse
Gene Type protein-coding
Description ATP-binding cassette, sub-family A (ABC1), member 3
Other Description ATP-binding cassette sub-family A member 3
Swissprots Q3U3L4 Q8R420
Accessions EDL22311 EDL22312 EDL22313 Q8R420 AF213394 AAF31433 AK007703 BAB25200 AK089316 AK089794 AK154698 BAE32771 AK165458 BAE38198 AK166355 AK168428 AK171239 AK186316 AY083616 AAL99380 BC006932 BC020183 BC038271 BC042663 AAH42663 BC047356 BC049911 BC056614 AAH56614 BC079617 AAH79617 CJ102288 CV784401 CX563731 XM_006524370 XP_006524433 XM_006524371 XP_006524434 XM_011246482 XP_011244784 NM_001039581 NP_001034670 NM_013855 NP_038883
Function Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol. {ECO:0000250}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Top Pathways ABC transporters

Anti-ATP-binding cassette sub-family A member 3 antibody [3C9] - ab24751 from Abcam

Prices $392.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3C9
IHC image of P180 Lamellar Body Protein staining in rat lung formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab24751, 10µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.
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