ADRB2

Gene Symbol	ADRB2
Entrez Gene	154
Alt Symbol	ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Species	Human
Gene Type	protein-coding
Description	adrenoceptor beta 2, surface
Other Description	adrenergic, beta-2-, receptor, surface|adrenoceptor beta 2 surface|beta-2 adrenergic receptor|beta-2 adrenoceptor|beta-2 adrenoreceptor|catecholamine receptor
Swissprots	Q9UCZ3 Q6P4D8 Q9UH95 Q8NEQ9 P07550 Q53GA6 Q9UMZ5 Q9UCZ1 Q4JG18 Q96EC3 B0LPE4 O14826 Q9UHA1 Q9UCZ0 Q6GMT4 O14825 O14823 O14824 B2R7X2 Q9UCZ2
Accessions	AAA88017 AAB82148 AAB82149 AAB82150 AAB82151 AAD48036 AAF17569 AAF20199 AAG35451 AAY88739 ABY87523 CAA68289 CBJ06537 EAW61798 P07550 AA886615 AK223025 BAD96745 AK313151 BAG35969 AY136741 AAN01267 BC012481 AAH12481 BC063486 AAH63486 BC073856 AAH73856 DA705141 KJ534762 AHW56402 M15169 AAA88014 X04827 CAA28511 NM_000024 NP_000015
Function	Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:19584355}; Multi-pass membrane protein {ECO:0000269|PubMed:19584355}. Note=Colocalizes with VHL at the cell membrane.
Top Pathways	Calcium signaling pathway, Endocytosis, Salivary secretion, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

β 2 -AR siRNA (h) - sc-39866 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

β 2 -AR shRNA Plasmid (h) - sc-39866-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

β 2 -AR shRNA (h) Lentiviral Particles - sc-39866-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU000621 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1598 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1598 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04686 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04686

ADRB2 siRNA (Human) - CRH0108 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

beta-2 Adrenergic R/ADRB2 RNAi - H00000154-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

ADRB2 - MBS8208935 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ADRB2 (NM_000024.5) - SHH232754 from Creative biogene Category siRNA Species Reactivities Human

ADRB2 shRNA Plasmid (Human) - CHH0108 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ADRB2 miRNA 3'UTR clone - MiUTR3H-00256 from Creative biogene Species Reactivities Human

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