Gene Symbol | Gp1ba |
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Entrez Gene | 14723 |
Alt Symbol | GPIba, GPIbalpha |
Species | Mouse |
Gene Type | protein-coding |
Description | glycoprotein 1b, alpha polypeptide |
Other Description | GP-Ib alpha|glycoprotein Ibalpha|platelet glycoprotein Ib alpha chain |
Swissprots | O35930 Q5SX47 |
Accessions | AAC53320 EDL12587 O35930 BC137765 AAI37766 XM_006532232 XP_006532295 XM_006537131 XP_006537194 NM_010326 NP_034456 |
Function | GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium. {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | ECM-receptor interaction, Hematopoietic cell lineage |
CD42b CRISPR/Cas9 KO Plasmid (m) - sc-420629 from Santa Cruz Biotechnology
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CD42b HDR Plasmid (m) - sc-420629-HDR from Santa Cruz Biotechnology
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CD42b Double Nickase Plasmid (m) - sc-420629-NIC from Santa Cruz Biotechnology
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CD42b Double Nickase Plasmid (m2) - sc-420629-NIC-2 from Santa Cruz Biotechnology
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CD42b CRISPR Activation Plasmid (m) - sc-420629-ACT from Santa Cruz Biotechnology
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CD42b CRISPR Activation Plasmid (m2) - sc-420629-ACT-2 from Santa Cruz Biotechnology
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CD42b Lentiviral Activation Particles (m) - sc-420629-LAC from Santa Cruz Biotechnology
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CD42b Lentiviral Activation Particles (m2) - sc-420629-LAC-2 from Santa Cruz Biotechnology
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CD42b siRNA (m) - sc-142201 from Santa Cruz Biotechnology
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CD42b shRNA Plasmid (m) - sc-142201-SH from Santa Cruz Biotechnology
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CD42b shRNA (m) Lentiviral Particles - sc-142201-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU055541 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN32646 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND32646 from Sigma-Aldrich
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GP1BA siRNA (Mouse) - CRM1636 from Cohesion Biosciences
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GP1BA - MBS8235356 from MyBioSource
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shRNA set against Mouse GP1BA (NM_010326.2) - SHH305522 from Creative biogene
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shRNA set against Mouse Gp1ba(NM_010326.2) - SHH094943 from Creative biogene
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Mouse GP1BA siRNA - orb281112 from Biorbyt
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GP1BA shRNA Plasmid (Mouse) - CHM1636 from Cohesion Biosciences
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GP1BA miRNA 3'UTR clone - MiUTR1M-05250 from Creative biogene
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