dib

Gene Symbol dib
Entrez Gene 45282
Alt Symbol 302a1, CG12028, CYP302A1, Cyp, Cyp302a1, Dib, Dmel\CG12028, l(3)64Ak, l(3)SH14, l(3)dib
Species Drosophila
Gene Type protein-coding
Description disembodied
Other Description CG12028-PA|cytochrome P450|dib-PA
Swissprots Q9VZJ0 Q059D3 Q9NGX9
Accessions AAF47831 Q9NGX9 BT029035 ABJ16968 NM_080071 NP_524810
Function Required for CNS development; negatively regulates glial cell division in the embryonic midline. Involved in the metabolism of insect hormones; responsible for ecdysteroid C22-hydroxylase activity. May be involved in the breakdown of synthetic insecticides. {ECO:0000269|PubMed:10976044, ECO:0000269|PubMed:12177427, ECO:0000269|PubMed:12676319}.
Subcellular Location Mitochondrion membrane {ECO:0000269|PubMed:14610274}.
Tissue Specificity Complex coexpression pattern of dib (disembodied) and sad (shade) in the early embryo that restricts to the prothoracic gland cells of the developing ring gland during late embryogenesis. In larvae and adult, coexpression is seen in prothoracic gland and follicle cells of the ovary. In adults, coexpression is seen in the follicle cells. {ECO:0000269|PubMed:10976044, ECO:0000269|PubMed:12177427}.
Top Pathways Insect hormone biosynthesis

Disembodied (N-term) antibody - AP09975PU-N from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Disembodied (C-term) antibody - AP09976PU-N from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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