| Gene Symbol | dib |
|---|---|
| Entrez Gene | 45282 |
| Alt Symbol | 302a1, CG12028, CYP302A1, Cyp, Cyp302a1, Dib, Dmel\CG12028, l(3)64Ak, l(3)SH14, l(3)dib |
| Species | Drosophila |
| Gene Type | protein-coding |
| Description | disembodied |
| Other Description | CG12028-PA|cytochrome P450|dib-PA |
| Swissprots | Q9VZJ0 Q059D3 Q9NGX9 |
| Accessions | AAF47831 Q9NGX9 BT029035 ABJ16968 NM_080071 NP_524810 |
| Function | Required for CNS development; negatively regulates glial cell division in the embryonic midline. Involved in the metabolism of insect hormones; responsible for ecdysteroid C22-hydroxylase activity. May be involved in the breakdown of synthetic insecticides. {ECO:0000269|PubMed:10976044, ECO:0000269|PubMed:12177427, ECO:0000269|PubMed:12676319}. |
| Subcellular Location | Mitochondrion membrane {ECO:0000269|PubMed:14610274}. |
| Tissue Specificity | Complex coexpression pattern of dib (disembodied) and sad (shade) in the early embryo that restricts to the prothoracic gland cells of the developing ring gland during late embryogenesis. In larvae and adult, coexpression is seen in prothoracic gland and follicle cells of the ovary. In adults, coexpression is seen in the follicle cells. {ECO:0000269|PubMed:10976044, ECO:0000269|PubMed:12177427}. |
| Top Pathways | Insect hormone biosynthesis |