RNASE2

Gene Symbol RNASE2
Entrez Gene 6036
Alt Symbol EDN, RAF3, RNS2
Species Human
Gene Type protein-coding
Description ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
Other Description RNase 2|RNase UpI-2|eosinophil-derived neurotoxin|non-secretory ribonuclease|ribonuclease 2|ribonuclease A F3|ribonuclease US
Swissprots Q9H2B7 P10153 Q52M39 Q9UCG7
Accessions AAG31577 AAG31578 AAG31579 AAG31580 AAG31581 AAG31582 AAG31583 AAG31584 AAG31585 CAA34546 CAA39459 CAC27640 CDG31919 EAW66435 P10153 BC093678 AAH93678 BC093680 AAH93680 BC096059 AAH96059 M24157 AAA52337 M28129 AAA50284 M30510 AAC82505 X55988 CAA39460 NM_002934 NP_002925
Function This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities. {ECO:0000269|PubMed:12578357, ECO:0000269|PubMed:3458170}.
Subcellular Location Lysosome {ECO:0000305}. Cytoplasmic granule. Note=Matrix of eosinophil's large specific granule.
Tissue Specificity Liver, lung, spleen, leukocytes and body fluids.

RNase 2 (T-13) - sc-165368 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

RNase 2 (C-13) - sc-165366 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Eosinophil derived neurotoxin antibody - ab103428 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Eosinophil derived neurotoxin antibody (ab103428) at 1/500 dilution + Human spleen tissue lysate at 50 µg

Anti-Eosinophil derived neurotoxin antibody - ab59750 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (clone 3H8) - LS-C84102 from LifeSpan Bioscience

Prices $695.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3H8

Anti-RNASE2 / EDN Antibody - LS-C122391 from LifeSpan Bioscience

Prices $405.00
Sizes 20 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (aa1-161) - LS-C131909 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (aa124-152, AP) - LS-C268333 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (aa124-152, APC) - LS-C285059 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (aa124-152, Biotin) - LS-C285061 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (aa124-152, FITC) - LS-C285062 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (aa124-152, Azide-free, HRP) - LS-C285063 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (aa124-152, PE) - LS-C285064 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody - LS-C285598 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (Biotin) - LS-C316886 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (HRP) - LS-C316888 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (FITC) - LS-C316887 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (aa124-152) - LS-C324703 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNASE2 / EDN Antibody (aa124-152) - LS-C158859 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of lysate from human spleen tissue lysate, using RNASE2 Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Eosinophil derived neurotoxin Antibody - NBP1-91872 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Eosinophil derived neurotoxin Antibody [NBP1-91872] Staining of human bone marrow shows strong cytoplasmic positivity in a subset of cells.

Eosinophil derived neurotoxin Antibody - H00006036-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Eosinophil derived neurotoxin Antibody [H00006036-B01P] - Analysis of RNASE2 expression in transfected 293T cell line by RNASE2 polyclonal antibody.  Lane1:RNASE2 transfected lysate(17.71 KDa). Lane2:Non-transfected lysate.

Eosinophil derived neurotoxin Antibody - H00006036-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-RNASE2 antibody produced in rabbit - HPA044983 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RNASE2: <B>Cat. No. HPA044983</B>: Immunohistochemical staining of human bone marrow shows strong cytoplasmic positivity in a subset of cells.

Anti-RNASE2 antibody produced in mouse - SAB1406393 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RNASE2: <B>Cat. No. SAB1406393</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~17.7 kDa using RNASE2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-RNASE2 antibody produced in rabbit - SAB1401337 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-RNASE2, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401337</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~18.35 kDa using human spleen lysate.
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