| Gene Symbol |
ATP5D
|
| Entrez Gene |
513
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
|
| Other Description |
ATP synthase subunit delta, mitochondrial|F-ATPase delta subunit|mitochondrial ATP synthase complex delta-subunit precusor|mitochondrial ATP synthase, delta subunit
|
| Swissprots |
D6W5Y3 Q6FG90 P30049
|
| Accessions |
AAC04304 EAW69531 EAW69532 EAW69533 EAW69534 P30049 AK094357 BC002389 AAH02389 BC004426 AAH04426 BC018079 AAH18079 BC018817 BC050458 BC058927 CR542218 CAG47014 S87916 AAA08055 S87918 ABB76284 X63422 CAA45016 X63423 CAA45017 NM_001001975 NP_001001975 NM_001687 NP_001678
|
| Function |
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP turnover in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
|
| Subcellular Location |
Mitochondrion. Mitochondrion inner membrane.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Oxidative phosphorylation
|
