CTPS1

Gene Symbol CTPS1
Entrez Gene 1503
Alt Symbol CTPS, IMD24
Species Human
Gene Type protein-coding
Description CTP synthase 1
Other Description CTP synthetase 1|UTP--ammonia ligase 1|cytidine 5'-triphosphate synthetase|cytidine 5-prime triphosphate synthetase
Swissprots B4DR64 Q96GK6 D3DPW1 P17812 Q5VW67
Accessions EAX07192 EAX07193 P17812 AI190299 AK130549 AK225899 AK297386 BAG59827 AK299122 BAG61176 AK303797 BAG64752 AK304817 BAH14260 BC009408 AAH09408 BQ642049 DA639348 DC313620 X52142 CAA36386 XM_005270536 XP_005270593 XM_006710390 XP_006710453 XM_006710391 XP_006710454 XM_011540821 XP_011539123 XM_011540822 XP_011539124 XR_946557 NM_001301237 NP_001288166 NM_001905 NP_001896 NR_125440
Function This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP- dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity. {ECO:0000269|PubMed:16179339, ECO:0000269|PubMed:24870241}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:24870241}.
Top Pathways Pyrimidine metabolism

CTPS1 (C-13) - sc-131474 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CTPS1 (K-21) - sc-101925 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
CTPS1 (K-21): sc-101925. Western blot analysis of CTPS1 expression in Hep G2 whole cell lysate.

CTPS1 (L-13) - sc-131475 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CTP synthase antibody - ab192988 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CTP synthase antibody (ab192988) at 0.1 µg/mlLane 1 : HeLa whole cell lysateLane 2 : 293T whole cell lysateLane 3 : Jurkat whole cell lysateLane 4 : TCMK1 whole cell lysateLane 5 : NIH 3T3 whole cell lysateLysates/proteins at 50 µg per lane.developed using the ECL technique

Anti-CTP synthase antibody [EPR8086(B)] - ab133743 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR8086(B)
All lanes : Anti-CTP synthase antibody [EPR8086(B)] (ab133743) at 1/1000 dilutionLane 1 : Raji cell lysateLane 2 : HepG2 cell lysateLane 3 : HeLa cell lysateLane 4 : U87-MG cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-Rabbit HRP at 1/2000 dilution

Anti-CTP synthase antibody - ab54579 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab54579 CTP synthase antibody at 1ug/ml.

Anti-CTPS Antibody (clone 2G7-1D10) - LS-C197001 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2G7-1D10

Anti-CTPS Antibody (aa60-109) - LS-C291691 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTPS Antibody (C-Terminus) - LS-C80812 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.

Anti-CTPS Antibody (aa156-205) - LS-C80811 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTPS antibody LS-C80811 was used in IHC to stain formalin-fixed, paraffin-embedded human liver.

Anti-CTPS Antibody (Lys109) - LS-C177243 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC of CTPS (K109 pAb in paraffin-embedded human liver carcinoma tissue.

Anti-CTPS Antibody (Internal, clone EPR8086(B)) - LS-C154681 from LifeSpan Bioscience

Host Rabbit
Clonality Monoclonal
Clone EPR8086(B)
Western blot analysis on (A) Raji, (B) HepG2, (C) HeLa, and (D) U87-MG cell lysates using anti-CTPS antibody.

CTP synthase Antibody - NBP1-52892 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CTP synthase Antibody [NBP1-52892] - Lanes: 1 : 45ug human capan1 cell lysate Primary, Antibody Dilution: 1 : 1000 Secondary Antibody: Anti-rabbit HRP Secondary, Antibody Dilution: 1 : 5000 Gene name: CTPS.

CTP synthase Antibody - NBP1-51201 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CTP synthase Antibody [NBP1-51201] - Analysis of CTP (K109) pAb in extracts from HuvEc cells

CTP synthase Antibody - 23370002 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: CTP synthase Antibody [23370002] - Moderate to strong cytoplasmic immunoreactivity, occasionally combined with nuclear positivity, was observed in normal and malignant tissues. Most glandular epithelia, cells of the central nervous system and renal tubuli displayed strong cytoplasmic staining. Most cases of colo-rectal, prostate and breast cancers showed strong cytoplasmic expression. Image and statement courtesy of the Human Protein Atlas (HPA).

CTP synthase Antibody (2G7-1D10) - H00001503-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G7-1D10
Western Blot: CTP synthase Antibody (2G7-1D10) [H00001503-M01] - Western Blot detection against Immunogen (90.75 KDa).

Anti-CTPS (416-430) antibody produced in rabbit - SAB1101072 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-CTPS (416-430) (RB): <B>Cat. No. SAB1101072</B>: Immunofluorescence of HUVEC cells using CTPS (416-430) (RB), Cat. No. SAB1101072 (red) at a 1:400 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-CTPS (AB1) antibody produced in rabbit - AV46069 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CTPS (ab1): <B>Cat. No. AV46069</B>: Immunohistochemistry of CTPS in Human Liver tissue with CTPS antibody at 4-8 μg/mL.

Anti-CTPS (AB2) antibody produced in rabbit - AV46070 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV46070</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 5.0 μg/mL in cell type HepG2

Monoclonal Anti-CTPS antibody produced in mouse - WH0001503M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G7-1D10
<B>Immunoblotting</B><BR/>Monoclonal Anti-CTPS, <B>Cat. No. WH0001503M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~90.75 kDa using immunogen protein lysate.

CTPS antibody - N-terminal region (ARP46069_T100) - ARP46069_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CTPS antibody - C-terminal region (ARP46070_T100) - ARP46070_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CTPS Antibody (OAAF05713) - OAAF05713 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CTPS antibody - 70R-16654 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Ctp Synthase antibody - 70R-1030 from Fitzgerald

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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