| Gene Symbol |
APG7
|
| Entrez Gene |
834630
|
| Alt Symbol |
ATAPG7, ATATG7, ATG7, AUTOPHAGY 7, AUTOPHAGY-RELATED 7, K15I22.10, K15I22_10
|
| Species |
Arabidopsis thaliana
|
| Gene Type |
protein-coding
|
| Description |
ubiquitin-like modifier-activating enzyme atg7
|
| Other Description |
-
|
| Swissprots |
Q9FJ46 Q94CD5
|
| Accessions |
AED95313 Q94CD5 AB073173 BAB88385 AF492761 AAM70190 AY034945 AAK59451 AY150456 AAN12897 NM_123958 NP_568652
|
| Function |
E1-like activating enzyme involved in the 2 ubiquitin- like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes. Involved in the senescence process. {ECO:0000269|PubMed:12070171}.
|
| Tissue Specificity |
Constitutively expressed (at protein level). {ECO:0000269|PubMed:12070171}.
|
| Top Pathways |
Regulation of autophagy
|