| Gene Symbol | Abcc1 |
|---|---|
| Entrez Gene | 17250 |
| Alt Symbol | Abcc1a, Abcc1b, MRP, Mdrap, Mrp1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| Other Description | ATP-binding cassette, sub-family C (CFTR/MRP), member 1a|ATP-binding cassette, sub-family C (CFTR/MRP), member 1b|LTC4 transporter|leukotriene C(4) transporter|multidrug resistance-associated protein 1|multiple drug resistance-associated protein |
| Swissprots | O35379 |
| Accessions | EDK97393 O35379 AF022908 AAB80938 AF213389 AAF31429 AI853854 AK029876 BAC26654 AK033750 AK045109 BAC32226 AK049174 BAC33586 AK051594 AK140421 AK150015 BAE29240 AK152781 AK162656 BC026509 BC090617 AAH90617 BP762240 XM_006521839 XP_006521902 NM_008576 NP_032602 |
| Function | Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o- glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. {ECO:0000269|PubMed:9281595}. |
| Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}. |
| Top Pathways | ABC transporters, Vitamin digestion and absorption, MicroRNAs in cancer, Sphingolipid signaling pathway |
Multidrug resistance-associated protein 1, Abcc1, Mouse, ELISA Kit - E1068m from ARP American Research Products
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Mouse MRP ELISA Kit - MM0348 from NeoScientific
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ATP-binding cassette, sub-family C (CFTR/MRP) , member 1, ELISA Kit - MBS9327817 from MyBioSource
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Mouse Abcc1 ELISA Kit - E045140 from Biobool
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Mouse MRP1 ELISA Kit - E060588 from Biobool
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Mouse MRP ELISA Kit - E060720 from Biobool
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ABCC1 ELISA Kit (Mouse) (OKEH03280) - OKEH03280 from Aviva Systems Biology
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Mouse MRP ELISA Kit - EMM0348 from ABclonal
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Mouse Multidrug resistance-associated protein 1 ELISA Kit - EK2685 from Signalway Antibody
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Mouse Multidrug resistance-associated protein 1 (ABCC1) ELISA Kit - AE23117MO from ARP American Research Products
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Multidrug resistance-associated protein 1, ELISA Kit - MBS9426522 from MyBioSource
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Multidrug resistance-associated protein 1, ELISA Kit - MBS2884807 from MyBioSource
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