PHF10

Gene Symbol PHF10
Entrez Gene 507648
Alt Symbol -
Species Bovine
Gene Type protein-coding
Description PHD finger protein 10
Other Description BAF45a|BRG1-associated factor 45a
Swissprots Q2T9V9
Accessions DAA25934 Q2T9V9 BC111243 AAI11244 NM_001038052 NP_001033141
Function Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron- specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulatin
Subcellular Location Nucleus {ECO:0000250}.

PHD finger protein 10, ELISA Kit - MBS9322205 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Bovine PHF10 ELISA Kit - E093465 from Biobool

Category ELISA Kit
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