| Gene Symbol |
NUP98
|
| Entrez Gene |
4928
|
| Alt Symbol |
ADIR2, NUP196, NUP96
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nucleoporin 98kDa
|
| Other Description |
GLFG-repeat containing nucleoporin|Nup98-Nup96|nuclear pore complex protein Nup98-Nup96|nucleoporin 98kD
|
| Swissprots |
Q8IUT2 Q9UF57 Q96E54 P52948 Q8WYB0 Q9UHX0 Q9Y6J5 Q9NT02 Q9Y6J4 Q9H3Q4
|
| Accessions |
BAB11850 EAX02561 EAX02562 EAX02563 EAX02564 EAX02565 EAX02566 P52948 AB040538 BAB18537 AF071076 AAD22395 AF071077 AAD22396 AF116074 AAF19342 AF231130 AAL56659 AK292882 BAF85571 AK301512 BAG63020 AL133601 CAB63736 AL137613 CAB70842 BC012906 AAH12906 BC041136 AAH41136 BG773331 BT007349 AAP36013 DB084013 U41815 AAC50366 XM_005252950 XP_005253007 XM_006718240 XP_006718303 XM_006718241 XP_006718304 XM_006718242 XP_006718305 XM_011520134 XP_011518436 XM_011520135 XP_011518437 XM_011520136 XP_011518438 XM_011520137 XP_011518439 XM_011520138 XP_011518440 XR_930872 XR_930873 NM_005387 NP_005378 NM_016320 NP_057404 NM_139131 NP_624357 NM_139132 NP_624358
|
| Function |
Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Nup98 and Nup96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. {ECO:0000269|PubMed:15229283}.
|
| Subcellular Location |
Nucleus. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Nucleus, nuclear pore complex. Note=Nup96 is localized to the nucleoplasmic side of the nuclear pore complex (NPC), at or near the nucleoplasmic basket. Dissociates from the dissasembled NPC structure early during prophase of mitosis. Colocalized with NUP153 and TPR to the nuclear basket of NPC. Detected in diffuse and discrete intranuclear foci. Remained localized to the nuclear membrane after poliovirus (PV) infection.
|
| Top Pathways |
RNA transport, Influenza A
|
