CA9

Gene Symbol CA9
Entrez Gene 768
Alt Symbol CAIX, MN
Species Human
Gene Type protein-coding
Description carbonic anhydrase IX
Other Description CA-IX|P54/58N|RCC-associated antigen G250|RCC-associated protein G250|carbonate dehydratase IX|carbonic anhydrase 9|carbonic dehydratase|membrane antigen MN|pMW1|renal cell carcinoma-associated antigen G250
Swissprots Q5T4R1 Q16790
Accessions CBL94025 EAW58359 Q16790 AI023541 AJ010588 CAB82444 AL554705 BC014950 AAH14950 DQ892208 ABM83134 DQ895404 ABM86330 EF122496 ABL67717 X66839 CAA47315 XM_006716869 XP_006716932 XM_006716870 XP_006716933 XR_428428 NM_001216 NP_001207
Function Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. {ECO:0000269|PubMed:18703501}.
Subcellular Location Nucleus {ECO:0000269|PubMed:8486430}. Nucleus, nucleolus {ECO:0000269|PubMed:8486430}. Cell membrane {ECO:0000269|PubMed:8486430}; Single-pass type I membrane protein {ECO:0000269|PubMed:8486430}. Cell projection, microvillus membrane {ECO:0000269|PubMed:8486430}; Single-pass type I membrane protein {ECO:0000269|PubMed:8486430}. Note=Found on the surface microvilli and in the nucleus, particularly in nucleolus.
Tissue Specificity Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.
Top Pathways Nitrogen metabolism

Active human Carbonic Anhydrase IX protein fragment - ab198056 from Abcam

Category Protein
Prices $837.00
Sizes 100 µg
Source Baculovirus infected sf9 cells
Species Human
Specific activity of ab198056 was determined to be 30,000 pmol/min/μg

Active human Carbonic Anhydrase IX protein fragment - ab174050 from Abcam

Category Protein
Prices $500.00
Sizes 50 µg
Source HEK 293 cells
Species Human
The purity of ab174050 was determined by reduced SDS-PAGE and stained overnight with Coomassie Blue. Lane 1: MW markers Lane 2: DTT-reduced ab174050 (predicted MW 41kDa) migrates as 53-54 kDa due to glycosylation.

Human Carbonic Anhydrase IX full length protein - ab114200 from Abcam

Category Protein
Prices $420.00
Sizes 10 µg
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab114200 at approximately 76.56kDa stained with Coomassie Blue.

Human Carbonic Anhydrase IX peptide - ab47011 from Abcam

Category Peptide
Prices $181.00
Sizes 100 µg

Human Carbonic Anhydrase IX protein fragment - ab186087 from Abcam

Category Protein
Prices $1,187.00
Sizes 100 µg
Source Baculovirus infected sf9 cells
Species Human

CA9 / Carbonic Anhydrase IX Antibody Blocking Peptide - LS-E7684 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CA9 / Carbonic Anhydrase IX Antibody Blocking Peptide - LS-E7687 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CA9 / Carbonic Anhydrase IX Blocking Peptide - LS-E7685 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

CA9 / Carbonic Anhydrase IX Blocking Peptide - LS-E7686 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Carbonic Anhydrase IX/CA9 Peptide - NB100-417PEP from Novus Biologicals

Category Peptide
Prices $99.00
Sizes 50 µl

Recombinant Human Carbonic Anhydrase IX/CA9 Protein - H00000768-P01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Carbonic Anhydrase IX/CA9 Peptide - P1704 from Novus Biologicals

Category Peptide
Species Human

Carbonic Anhydrase IX/CA9 Peptide - P1703 from Novus Biologicals

Category Peptide
Species Human

CA9-Antibody-Center-Blocking-Peptide - BP5000e from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CA9-Antibody-N-term-Blocking-Peptide - BP5000d from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CA9-Antibody-Center-Blocking-Peptide - BP5000b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CA9-Antibody-N-term-Blocking-Peptide - BP5000a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Carbonic Anhydrase IX, CF - 2188-CA-010 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived, Pro59-Asp414, with a C-terminal 10-His tag

Recombinant human Carbonic anhydrase 9 (OPCA00603) - OPCA00603 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

Human Carbonic protein - orb245255 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Mouse CA9 His tag protein - orb83960 from Biorbyt

Category Protein
Prices $323.00, $527.00
Sizes 10 μg, 20 μg
Source Mouse
Species Human
SDS-PAGE analysis of mouse CA9 His tag protein

Human CA9 Fc tag protein - orb82882 from Biorbyt

Category Protein
Prices $323.00, $527.00
Sizes 10 μg, 20 μg
Source Human
Species Human
SDS-PAGE analysis of human CA9 Fc tag protein

Canine CA9 protein - orb138291 from Biorbyt

Category Protein
Source Human Cells
SDS-PAGE analysis of canine CA9 protein

Human CA9 His tag protein - orb82883 from Biorbyt

Category Protein
Prices $323.00, $527.00
Sizes 10 μg, 20 μg
Source Human
Species Human
SDS-PAGE analysis of human CA9 His tag protein

Canine CA9 protein (His Tag) - orb138292 from Biorbyt

Category Protein
Prices $323.00, $527.00
Sizes 10 μg, 20 μg
Source Human Cells
SDS-PAGE analysis of canine CA9 protein (His Tag)
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