| Gene Symbol |
GBGT1
|
| Entrez Gene |
26301
|
| Alt Symbol |
A3GALNT, FS, UNQ2513
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
|
| Other Description |
Forssman glycolipid synthetase (FS)|forssman glycolipid synthase-like protein
|
| Swissprots |
Q8N5D6 A8K633 Q5T7U9 Q5T7V1 B2RA95 B7Z8S5 Q45F07 Q9UKI5 Q8N2K4
|
| Accessions |
AAZ38721 CAF86142 CCD30587 CCD30588 CCD30589 CCD30590 CCD30591 EAW88043 EAW88044 EAW88045 EAW88046 EAW88047 Q8N5D6 AK074639 BAC11106 AK074944 AK291498 BAF84187 AK303825 BAH14061 AK307687 AK314097 BAG36792 AY358175 AAQ88542 BC032499 AAH32499 BI906086 CA397865 HY315485 NM_001282629 NP_001269558 NM_001282632 NP_001269561 NM_001288572 NP_001275501 NM_001288573 NP_001275502 NM_021996 NP_068836
|
| Function |
Catalyzes the formation of some glycolipid via the addition of N-acetylgalactosamine (GalNAc) in alpha-1,3-linkage to some substrate. Glycolipids probably serve for adherence of some pathogens.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Widely expressed. Expressed at higher level in placenta, ovary and peripheral blood leukocyte, whereas it is weakly expressed in liver, thymus, and testis. {ECO:0000269|PubMed:10506200}.
|
| Top Pathways |
Glycosphingolipid biosynthesis - globo series
|